IMPLICATIONS: Surgery and cardiopulmonary bypass lead to a potent stress response
which might be associated with an imbalance of the immune system and increased risk for …

Background Clonidine and dexmedetomidine are alpha-2 agonists with beneficial effect on
the hemodynamic response to laryngoscopy and intubation. The present study was …

IMPLICATIONS: In 80 patients undergoing carotid endarterectomy under regional
anesthesia, supplemental clonidine infusion (1 μg· kg− 1· h− 1) suppressed the …

Background: Subarachnoid hemorrhage is often accompanied by systemic complications
and cerebral vasospasm. Elevated levels of circulating catecholamines may be involved in …

Background Dexmedetomidine-induced bradycardia or hypotension has recently attracted
considerable attention because of potentially grave consequences, including sinus arrest …

Despite the fact that coronary artery bypass grafting surgery (CABG) with cardiopulmonary
bypass (CPB) prolongs life and reduces symptoms in patients with severe coronary artery …

Study Objectives: To investigate whether a single preoperative IV dose of clonidine blunts
the hemodynamic and hyperadrenergic responses not only to intubation, but also to …

In this prospective, nonblind study, we report the use of clonidine during orthotopic liver
transplantation (OLT). Twenty adult patients in a stable medical condition were studied …

Clonidine is classified as an imidazoline and it is the prototypical alpha-2 receptor agonists.
It has been used for several years to treat hypertension. It has also been used,“off label”, for …