Methods In a randomized, double-blind study, effects of clonidine (150 μg orally), midazolam
(7.5 mg orally) and placebo administered 60–90 min prior to estimated anaesthesia …

We studied the effects of clonidine (0.5 mg/kg) on hormonal stress response and antioxidant
enzymes cold restraint-induced gastric lesions in rats. Rats in the study group were given …

Study Objective: To examine how premedication with clonidine affects opioid use,
hemodynamic effects, hormonal responses, and recovery effects. Design: Double-blind …

The effects of intravenous and epidural clonidine, 4 μg kg− 1, combined with epidural
morphine, 40 μg kg− 1, on the neuro-endocrine and immune stress responses to thoracic …

Background and objectives: The aim of this study was to evaluate the effects of remote
ischemic preconditioning by brief ischemia of unilateral hind limb when combined with …

We investigated the influence of intravenous clonidine 2, 4 and 6 μg kg− 1 on the
electroencephalogram and on the minimal alveolar concentration of isoflurane in 40 patients …

DISCUSSION Our search of the literature reveals 1 previous case report of polyuric
syndrome in a patient receiving dexmedetomidine. 3 In that case, the patient received …

Tizanidine, an α 2-adrenoceptor agonist, has an antinociceptive effect in animals. In humans
premedicated with oral tizanidine, the increase in blood pressure associated with …

Clonidine is a preferential alpha-2 agonist drug that has been used for over 35 years to treat
hypertension. Recently, it has also been used as a preoperative medication and as a …

The study evaluated the effects of premedication with intravenous clonidine on thiopental or
propofol requirements for induction and haemodynamic changes associated with both …