Clostridioides difficile (formerly Clostridium difficile) infection is a substantial health and
economic burden worldwide. Great strides have been made over the past several years in …

Since the discovery of the Escherichia coli leucine-responsive regulatory protein (Lrp)
almost 50 years ago, hundreds of Lrp homologs have been discovered, occurring in 45% of …

Clostridioides difficile (formerly Clostridium difficile) colonizes the gastrointestinal tract
following disruption of the microbiota and can initiate a spectrum of clinical manifestations …

Clostridioides difficile infection (CDI) may recur in approximately 10–30% of patients, and
the risk of recurrence increases with each successive recurrence, reaching up to 65%. C …

Short-chain fatty acids (SCFAs) are products of bacterial fermentation that help maintain
important gut functions such as maintenance of the intestinal barrier, cell signaling, and …

Clostridioides difficile (CD), a nosocomial gut pathogen, produces two major exotoxins,
TcdA and TcdB, which disrupt the gut epithelial barrier and induce inflammatory/immune …

Anthropogenic activities and climate change profoundly impact water quality, leading to a
concerning increase in the prevalence and abundance of bacterial pathogens across …

Vibrio alginolyticus is the main pathogen causing vibriosis in pearl gentian grouper, which
has caused significant financial losses to farmers. To develop a sustainable and effective …

The appY gene has been characterised as conferring resistance to a novel series of
antimicrobial benzimidazole derivatives in E. coli MC1061 cells when expressed in high …

Leucine-responsive regulatory protein (Lrp) is an essential transcriptional regulator in
prokaryotes. However, the regulatory role of lrp in Vibrio alginolyticus has still not been …