Routes of drug administration and the corresponding physicochemical characteristics of a
given route play significant roles in therapeutic efficacy and short term/long term biological …

Transdermal drug delivery using microneedles is increasingly gaining interest due to the
issues associated with oral drug delivery routes. Gastrointestinal route exposes the drug to …

Proteins and peptides (PPs) have gradually become more attractive therapeutic molecules
than small molecular drugs due to their high selectivity and efficacy, but fewer side effects …

The development of microneedles (MNs) assisted drug delivery technologies have been
highly active for more than two decades. The minimally invasive and self-administered MN …

Biofilms in chronic wounds, including diabetic foot ulcers, pressure ulcers, and venous leg
ulcers, pose a major challenge to wound management. Herein, we report a Janus-type …

Microneedles technology is a powerful platform to achieve efficient transdermal delivery of
bioactive molecules for local or systemic therapies attributing to their minimally invasive …

Despite the promise of immune checkpoint blockade (ICB) therapy against cancer,
challenges associated with low objective response rates and severe systemic side effects …

The remarkable appeal of microneedle controlled-release systems has captivated both the
academic community and pharmaceutical industry due to their great potential for achieving …

Microneedle (MN) delivery system has been greatly developed to deliver drugs into the skin
painlessly, noninvasively, and safety. In the past several decades, various types of MNs …

Although transdermal drug delivery systems (DDS) offer numerous benefits for patients,
including the avoidance of both gastric irritation and first-pass metabolism effect, as well as …