Oxidative stress and inflammation generated DNA damage by exposure to air pollution particles

P Møller, PH Danielsen, DG Karottki, K Jantzen… - … research/Reviews in …, 2014 - Elsevier
Generation of oxidatively damaged DNA by particulate matter (PM) is hypothesized to occur
via production of reactive oxygen species (ROS) and inflammation. We investigated this …

Role of oxidative damage in toxicity of particulates

P Møller, NR Jacobsen, JK Folkmann… - Free radical …, 2010 - Taylor & Francis
Particulates are small particles of solid or liquid suspended in liquid or air. In vitro studies
show that particles generate reactive oxygen species, deplete endogenous antioxidants …

Targeting chelatable iron as a therapeutic modality in Parkinson's disease

D Devos, C Moreau, JC Devedjian, J Kluza… - Antioxidants & redox …, 2014 - liebertpub.com
Aims: The pathophysiological role of iron in Parkinson's disease (PD) was assessed by a
chelation strategy aimed at reducing oxidative damage associated with regional iron …

Synergistic and antagonistic interactions among the particulate matter components in generating reactive oxygen species based on the dithiothreitol assay

H Yu, J Wei, Y Cheng, K Subedi… - Environmental science & …, 2018 - ACS Publications
We assessed the interactions among the particulate matter (PM) components in generating
the reactive oxygen species (ROS) based on a dithiothreitol (DTT) assay. We started with the …

[HTML][HTML] Fine particulate matter in acute exacerbation of COPD

L Ni, CC Chuang, L Zuo - Frontiers in physiology, 2015 - frontiersin.org
Chronic obstructive pulmonary disease (COPD) is a common airway disorder. In particular,
acute exacerbations of COPD (AECOPD) can significantly reduce pulmonary function. The …

Air pollution-derived PM2. 5 impairs mitochondrial function in healthy and chronic obstructive pulmonary diseased human bronchial epithelial cells

B Leclercq, J Kluza, S Antherieu, J Sotty… - Environmental …, 2018 - Elsevier
In order to clarify whether the mitochondrial dysfunction is closely related to the cell
homeostasis maintenance after particulate matter (PM 2.5) exposure, oxidative …

Proinflammatory effects and oxidative stress within human bronchial epithelial cells exposed to atmospheric particulate matter (PM2. 5 and PM> 2.5) collected from …

BF Cachon, S Firmin, A Verdin, L Ayi-Fanou… - Environmental …, 2014 - Elsevier
After particulate matter (PM) collection in Cotonou (Benin), a complete physicochemical
characterization of PM 2.5 and PM> 2.5 was led. Then, their adverse health effects were …

Pro-inflammatory effects and oxidative stress in lung macrophages and epithelial cells induced by ambient particulate matter

S Michael, M Montag, W Dott - Environmental pollution, 2013 - Elsevier
The objective of this study was to compare the toxicological effects of different source-related
ambient PM10 samples in regard to their chemical composition. In this context we …

Reducing the burden of anaemia in Indian women of reproductive age with clean-air targets

E Chaudhary, S Dey, S Ghosh, S Sharma… - Nature …, 2022 - nature.com
India has one of the highest (53%) global prevalences of anaemia among women of
reproductive age (WRA, 15–49 years). Long-term exposure to ambient fine particulate …

Chemical and organic characteristics of PM2. 5 particles and their in-vitro cytotoxic effects on lung cells: The Middle East dust storms in Ahvaz, Iran

G Goudarzi, M Shirmardi, A Naimabadi… - Science of the total …, 2019 - Elsevier
There are very few reports about the effect of PM 2.5 particles carried by the Middle East
dust storms on lung cells. This study aimed to investigate the chemical properties and in …