Atherosclerosis is a chronic inflammatory process that, in the presence of hyperlipidaemia,
promotes the formation of atheromatous plaques in large vessels of the cardiovascular …

Abstract Ischemia/reperfusion (I/R) injury is a common cause of liver dysfunction during
hepatectomy, liver transplantation procedures and in generalized shock. Although effort has …

Myogenic microRNAs (myomiRs) that are specifically expressed in cardiac and skeletal
muscle are highly relevant to myogenic development and diseases. Discovery and …

Ageing is associated with a progressive loss of skeletal muscle mass, quality and function—
sarcopenia, associated with reduced independence and quality of life in older generations …

Mesenchymal stem cells (MSCs) have been proposed as a promising cell population for cell
therapy and regenerative medicine applications. However, the low retention and poor …

Regular exercise, particularly resistance training (RT), is the only therapy known to
consistently improve muscle strength and quality (force per unit of mass) in older persons …

Aromatase converts androgens into estrogens and its expression within adipose stromal
cells (ASCs) is believed to be the major driver of estrogen-dependent cancers in older …

Sarcopenia, the progressive loss of muscle mass and dysfunction, universally affects the
elderly and is closely associated with frailty and reduced quality of life. Despite the inevitable …

Background Oxidative stress is crucial player in skeletal muscle atrophy pathogenesis. S-
allyl cysteine (SAC), an organosulfur compound of Allium sativum, possesses broad …

Unacylated ghrelin (UnGhr) exerts several beneficial actions on vascular function. The aim
of this study was to assess the effects of UnGhr on high-fat induced endothelial dysfunction …