Unacylated ghrelin enhances satellite cell function and relieves the dystrophic phenotype in duchenne muscular dystrophy mdx model

S Reano, E Angelino, M Ferrara, V Malacarne… - Stem Cells, 2017 - academic.oup.com
Muscle regeneration depends on satellite cells (SCs), quiescent precursors that, in
consequence of injury or in pathological states such as muscular dystrophies, activate …

Angiogenesis in diabetic mouse model with critical limb ischemia; cell and gene therapy

SL Asadi-Yousefabad, P Nammian, SMB Tabei… - Microvascular …, 2022 - Elsevier
Purpose Critical limb ischemia (CLI) is the most severe manifestation of peripheral artery
disease that diabetes mellitus is one of its major risk factors. MiR-126 as an endothelial cells …

Prediction of key genes and miRNAs responsible for loss of muscle force in patients during an acute exacerbation of chronic obstructive pulmonary disease

Y Duan, M Zhou, J Xiao, C Wu… - International …, 2016 - spandidos-publications.com
The present study aimed to identify genes and microRNAs (miRNAs or miRs) that were
abnormally expressed in the vastus lateralis muscle of patients with acute exacerbations of …

Ret finger protein mediates Pax7-induced ubiquitination of MyoD in skeletal muscle atrophy

H Joung, GH Eom, N Choe, HM Lee, JH Ko, DH Kwon… - Cellular …, 2014 - Elsevier
Skeletal muscle atrophy results from the net loss of muscular proteins and organelles and is
caused by pathologic conditions such as nerve injury, immobilization, cancer, and other …

Ghrelin knockout mice display defective skeletal muscle regeneration and impaired satellite cell self-renewal

E Angelino, S Reano, A Bollo, M Ferrara, M De Feudis… - Endocrine, 2018 - Springer
Purpose Muscle regeneration depends on satellite cells (SCs), quiescent precursors that, in
consequence of injury or pathological states such as muscular dystrophies, activate …

Expression and regulation of glucocorticoid-induced leucine zipper in the developing anterior pituitary gland

LE Ellestad, SA Malkiewicz, HD Guthrie… - Journal of …, 2009 - jme.bioscientifica.com
The role of the adipocyte-derived factor visfatin in metabolism remains controversial,
although some pancreatic β-cell-specific effects have been reported. This study investigated …

Simultaneous miRNA and mRNA transcriptome profiling of differentiating equine satellite cells treated with gamma-oryzanol and exposed to hydrogen peroxide

KA Chodkowska, A Ciecierska, K Majchrzak… - Nutrients, 2018 - mdpi.com
Gamma-oryzanol (GO) is a popular supplement for performance horses, dogs, and humans.
Previous studies indicated that GO supplementation decreases creatine kinase activity and …

Antifibrotic activity of acylated and unacylated ghrelin

E Angelino, S Reano, M Ferrara… - International Journal …, 2015 - Wiley Online Library
Fibrosis can affect almost all tissues and organs, it often represents the terminal stage of
chronic diseases, and it is regarded as a major health issue for which efficient therapies are …

Control of DNA integrity in skeletal muscle under physiological and pathological conditions

Y Bou Saada, V Zakharova, B Chernyak, C Dib… - Cellular and molecular …, 2017 - Springer
Skeletal muscle is a highly oxygen-consuming tissue that ensures body support and
movement, as well as nutrient and temperature regulation. DNA damage induced by …

Dysregulation of ghrelin in diabetes impairs the vascular reparative response to hindlimb ischemia in a mouse model; clinical relevance to peripheral artery disease

JPH Neale, JT Pearson, KN Thomas, H Tsuchimochi… - Scientific reports, 2020 - nature.com
Type 2 diabetes is a prominent risk factor for peripheral artery disease (PAD). Yet, the
mechanistic link between diabetes and PAD remains unclear. This study proposes that …