Drug addiction is a chronic and debilitating disease that is considered a global health
problem. Various cell types in the brain are involved in the progression of drug addiction …

This paper is the forty-fourth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

Abstract In 2000, a subanesthetic dose (0.5 mg/kg iv) of the dissociative anesthetic ketamine
was reported to have both rapid and robust antidepressant effects in patients diagnosed with …

Central nervous system (CNS) diseases have been a growing threat to the health of
humanity, emphasizing the urgent need of exploring the pathogenesis and therapeutic …

Although targeted radiotherapy (RT) is integral to the increasing survival of cancer patients,
it has significant side-effects, the cellular and molecular mechanisms of which are not fully …

Abstract The Opioid Growth Factor–Opioid Growth Factor Receptor axis was identified
nearly 30 years ago in our laboratory when we demonstrated that an endogenous opioid …