Clinical applications and anticancer effects of antimicrobial peptides: from bench to bedside

A Jafari, A Babajani, R Sarrami Forooshani… - Frontiers in …, 2022 - frontiersin.org
Cancer is a multifaceted global health issue and one of the leading causes of death
worldwide. In recent years, medical science has achieved great advances in the diagnosis …

[HTML][HTML] MicroRNA-based therapy for glioblastoma: Opportunities and challenges

Q Lei, Y Yang, W Zhou, W Liu, Y Li, N Qi, Q Li… - European Journal of …, 2023 - Elsevier
Glioblastoma (GBM) is the most common and aggressive primary malignant brain tumor and
is characterized by high mortality and morbidity rates and unpredictable clinical behavior …

Hypoxia‐inducible lncRNA MIR210HG interacting with OCT1 is involved in glioblastoma multiforme malignancy

KH Ho, CM Shih, AJ Liu, KC Chen - Cancer science, 2022 - Wiley Online Library
An insufficient oxygen supply within the intratumoral environment, also known as hypoxia,
induces glioblastoma multiforme (GBM) invasion, stemness, and temozolomide (TMZ) drug …

MicroRNA in brain pathology: Neurodegeneration the other side of the brain cancer

J Godlewski, J Lenart, E Salinska - Non-coding RNA, 2019 - mdpi.com
The mammalian brain is made up of billions of neurons and supporting cells (glial cells),
intricately connected. Molecular perturbations often lead to neurodegeneration by …

Transcription factor and miRNA interplays can manifest the survival of ccRCC patients

S Qin, X Shi, C Wang, P Jin, F Ma - Cancers, 2019 - mdpi.com
Clear cell renal cell carcinoma (ccRCC) still remains a higher mortality rate in worldwide.
Obtaining promising biomakers is very crucial for improving the diagnosis and prognosis of …

Histone demethylase UTX/KDM6A enhances tumor immune cell recruitment, promotes differentiation and suppresses medulloblastoma

J Yi, X Shi, Z Xuan, J Wu - Cancer letters, 2021 - Elsevier
The deregulation of epigenetic pathways has been implicated as a critical step in
tumorigenesis including in childhood brain tumor medulloblastoma. The H3K27me3 …

[HTML][HTML] Identification of prognostic genes in the acute myeloid leukemia microenvironment

S Huang, B Zhang, W Fan, Q Zhao, L Yang… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
The tumor microenvironment (TME) has a strong influence on the progression, therapeutic
response, and clinical outcome of acute myeloid leukemia (AML), one of the most common …

miRNA signature in glioblastoma: Potential biomarkers and therapeutic targets

O Rezaei, K Honarmand, S Nateghinia, M Taheri… - Experimental and …, 2020 - Elsevier
MicroRNAs (miRNAs) are transcripts with sizes of about 22 nucleotides, which are produced
through a multistep process in the nucleus and cytoplasm. These transcripts modulate the …

Efficient delivery of anti-miR-210 using Tachyplesin, a cell penetrating peptide, for glioblastoma treatment

A Jana, P Narula, A Chugh, R Kulshreshtha - International Journal of …, 2019 - Elsevier
The levels of microRNAs (miRNAs) are altered in various diseases including glioblastoma
(GBM) and this alteration may have widespread effects on various hallmarks of cancer cells …

Identification of genes of prognostic value in the ccRCC microenvironment from TCGA database

B Wan, B Liu, Y Huang, C Lv - Molecular genetics & genomic …, 2020 - Wiley Online Library
Background Clear cell renal cell carcinoma (ccRCC) is the most common pathological
subtype of renal cell carcinoma. Bioinformatics analyses were used to screen candidate …