Pathogenic mechanisms associated with different clinical courses of multiple sclerosis

H Lassmann - Frontiers in immunology, 2019 - frontiersin.org
In the majority of patients multiple sclerosis starts with a relapsing remitting course (RRMS),
which may at later times transform into secondary progressive disease (SPMS). In a minority …

Molecular biomarkers in multiple sclerosis

T Ziemssen, K Akgün, W Brück - Journal of neuroinflammation, 2019 - Springer
Multiple sclerosis (MS) is an inflammatory-neurodegenerative disease of the central nervous
system presenting with significant inter-and intraindividual heterogeneity. However, the …

Cellular and molecular evidence of multiple sclerosis diagnosis and treatment challenges

Z Khan, GD Gupta, S Mehan - Journal of clinical medicine, 2023 - mdpi.com
Multiple sclerosis (MS) is a chronic autoimmune disease that impacts the central nervous
system and can result in disability. Although the prevalence of MS has increased in India …

Neurofilament levels, disease activity and brain volume during follow-up in multiple sclerosis

I Håkansson, A Tisell, P Cassel, K Blennow… - Journal of …, 2018 - Springer
Background There is a need for clinically useful biomarkers of disease activity in clinically
isolated syndrome (CIS) and relapsing remitting MS (RRMS). The aim of this study was to …

Tear biomarkers in Alzheimer's and Parkinson's diseases, and multiple sclerosis: implications for diagnosis (systematic review)

A Król-Grzymała, E Sienkiewicz-Szłapka… - International Journal of …, 2022 - mdpi.com
Biological material is one of the most important aspects that allow for the correct diagnosis of
the disease, and tears are an interesting subject of research because of the simplicity of …

Multiple sclerosis: inflammatory and neuroglial aspects

G Papiri, G D'Andreamatteo, G Cacchiò, S Alia… - Current Issues in …, 2023 - mdpi.com
Multiple sclerosis (MS) represents the most common acquired demyelinating disorder of the
central nervous system (CNS). Its pathogenesis, in parallel with the well-established role of …

Psychotic disorders as a framework for precision psychiatry

F Coutts, N Koutsouleris, P McGuire - Nature Reviews Neurology, 2023 - nature.com
People with psychotic disorders can show marked interindividual variations in the onset of
illness, responses to treatment and relapse, but they receive broadly similar clinical care …

Gut-microbiota, and multiple sclerosis: background, evidence, and perspectives

C Altieri, B Speranza, MR Corbo, M Sinigaglia… - Nutrients, 2023 - mdpi.com
Many scientific studies reveal a significant connection between human intestinal microbiota,
eating habits, and the development of chronic-degenerative diseases; therefore, alterations …

Experimental and clinical biomarkers for progressive evaluation of neuropathology and therapeutic interventions for acute and chronic neurological disorders

DS Reddy, HN Abeygunaratne - International Journal of Molecular …, 2022 - mdpi.com
This article describes commonly used experimental and clinical biomarkers of neuronal
injury and neurodegeneration for the evaluation of neuropathology and monitoring of …

Role of Chitinase 3–like 1 as a biomarker in multiple sclerosis: a systematic review and meta-analysis

S Floro, T Carandini, AM Pietroboni… - Neurology …, 2022 - AAN Enterprises
Background and Objectives Multiple sclerosis (MS) is an autoimmune disease confined in
the CNS, and its course is frequently subtle and variable. Therefore, predictive biomarkers …