Can antibodies be “vegan”? A guide through the maze of today's antibody generation methods

S Dübel - Mabs, 2024 - Taylor & Francis
There is no doubt that today's life sciences would look very different without the availability of
millions of research antibody products. Nevertheless, the use of antibody reagents that are …

Cellular immunotherapies and immune cell depleting therapies in inflammatory bowel diseases: the next magic bullet?

MF Neurath, BE Sands, F Rieder - Gut, 2024 - gut.bmj.com
Despite significant advances in biologic and small molecule treatments and the emergence
of combination therapies to treat inflammatory bowel diseases (IBD) a large unmet need …

[HTML][HTML] A Comprehensive ddPCR Strategy for Sensitive and Reliable Monitoring of CAR-T Cell Kinetics in Clinical Applications

G Wiedemann, U Bacher, R Joncourt, F Solly… - International Journal of …, 2024 - mdpi.com
In this study, we present the design, implementation, and successful use of digital droplet
PCR (ddPCR) for the monitoring of chimeric antigen receptor T-cell (CAR-T) expansion in …

Specific antitumor activity of anti-CA125 CAR-T lymphocytes against CA125-positive and CA125-negative cells

TM Kulinich, YY Kiseleva, AM Shishkin… - Sechenov Medical …, 2024 - sechenovmedj.com
Aim. To evaluate the antitumor efficacy of our developed drug based on cytotoxic T
lymphocytes genetically modified with a chimeric antigen receptor (CAR) specific to the …

[PDF][PDF] College of Nursing, AIIMS, Rishikesh, Uttarakhand, India

M Parveen - twjms.wocsi.org
Several local and systemic treatments have been established in the past year, but because
the disease situation is heterogeneous, their results have been restricted. Research on …