Depression is one of the most common psychiatric conditions, characterized by significant
and persistent depressed mood and diminished interest, and often coexists with various …

The discovery of the robust antidepressant actions of ketamine is regarded as one of the
greatest advancements in depression treatment in the past 60 years. Recent findings have …

Numerous studies have emphasised the importance of the gut microbiota during early life
and its role in modulating neurodevelopment and behaviour. Epidemiological studies have …

Probiotics are currently the subject of intensive research pursuits and also represent a multi-
billion-dollar global industry given their vast potential to improve human health. In addition …

Background Due to the rising cases of treatment-refractory affective disorders, the discovery
of newer therapeutic approaches is needed. In recent times, probiotics have garnered …

Depressed mice have lower numbers of microglia in the dentate gyrus (DG). Reversal of this
decline by a single low dose of lipopolysaccharide (LPS) may have antidepressant effects …

Depression is a common and severe mental disease that places a heavy burden on human
society, which can lead to decreased cognitive function, energy loss, insomnia, and even …

Parkinson's disease (PD) is a complicated neurodegenerative disease, characterized by the
accumulation of α-synuclein (α-syn) in Lewy bodies and neurites, and massive loss of …

Major depressive disorder (MDD) is a highly prevalent and disabling disorder. Despite the
many hypotheses proposed to understand the molecular pathophysiology of depression, it is …

Objective We aimed to conduct a systematic review and meta-analysis of observational
studies examining the relationship between ultra-processed food (UPF) consumption and …