Drug resistance in the HIV-1-infected paediatric population worldwide: a systematic review

P Rojas Sánchez, A Holguín - Journal of Antimicrobial …, 2014 - academic.oup.com
Background Drug resistance monitoring of the paediatric HIV-1-infected population is
required to optimize treatment success and preserve future treatment options. Objectives To …

High rates of virological failure and drug resistance in perinatally HIV‐1‐infected children and adolescents receiving lifelong antiretroviral therapy in routine clinics in …

M Salou, AY Dagnra, C Butel, N Vidal… - Journal of the …, 2016 - Wiley Online Library
Introduction Antiretroviral treatment (ART) has been scaled up over the last decade but
compared to adults, children living with HIV are less likely to receive ART. Moreover …

The status of HIV-1 resistance to antiretroviral drugs in sub-Saharan Africa

RL Hamers, I Derdelinckx, M van Vugt… - Antiviral …, 2008 - journals.sagepub.com
Access to highly active antiretroviral therapy (HAART) for persons infected with HIV in sub-
Saharan Africa has greatly improved over the past few years. However, data on long-term …

Reverse transcriptase inhibitors as potential colorectal microbicides

C Herrera, M Cranage, I McGowan… - Antimicrobial Agents …, 2009 - Am Soc Microbiol
We investigated whether reverse transcriptase (RT) inhibitors (RTI) can be combined to
inhibit human immunodeficiency virus type 1 (HIV-1) infection of colorectal tissue ex vivo as …

Long-term outcome of children receiving antiretroviral treatment in rural South Africa: substantial virologic failure on first-line treatment

RE Barth, HA Tempelman, E Smelt… - The Pediatric …, 2011 - journals.lww.com
Background: Long-term (> 12 months follow-up) virologic data of children receiving
antiretroviral therapy (ART) in Sub-Saharan Africa are limited. Data from rural areas are …

Long-term effectiveness of combination antiretroviral therapy and prevalence of HIV drug resistance in HIV-1–infected children and adolescents in Rwanda

PR Mutwa, KR Boer, J Rusine… - The Pediatric …, 2014 - journals.lww.com
Objective: To determine the long-term outcomes of treatment and prevalence of genotypic
drug resistance in children and adolescents on combination antiretroviral therapy. Methods …

Long-term virologic response and genotypic resistance mutations in HIV-1 infected Kenyan children on combination antiretroviral therapy

DC Wamalwa, DA Lehman… - JAIDS Journal of …, 2013 - journals.lww.com
Background: HIV-infected children may require the use of combination antiretroviral
treatment (cART) into adulthood. However, regimens are limited to first line and second line …

HIV type 1 subtype diversity and drug resistance among HIV type 1-infected Kenyan patients initiating antiretroviral therapy

RW Lihana, SA Khamadi, K Lubano… - AIDS research and …, 2009 - liebertpub.com
The treatment of HIV-1 infection with antiretroviral drugs has greatly improved the survival of
those who are infected. However, HIV-1 diversity and drug resistance are major challenges …

Drug resistance among drug-naive and first-line antiretroviral treatment-failing children in Cameroon

J Fokam, R Salpini, MM Santoro, V Cento… - The Pediatric …, 2011 - journals.lww.com
Background: Scale-up to antiretroviral therapy (ART) requires surveillance for HIV drug
resistance. With the goal of attaining 100% pediatric ART coverage in Cameroon, strategies …

High rate of antiretroviral drug resistance mutations in HIV type 1-infected Senegalese children in virological failure on first-line treatment according to the World …

K Kebe, M Thiam, NR Diagne Gueye… - AIDS research and …, 2013 - liebertpub.com
The rates of virological failure (VF) and HIV-1 drug resistance were evaluated in a cross-
sectional study in HIV-1-infected children living in Dakar, and taking antiretroviral treatment …