[HTML][HTML] Hypoxic adaptation of mitochondria and its impact on tumor cell function

M Benej, I Papandreou, NC Denko - Seminars in Cancer Biology, 2024 - Elsevier
Mitochondria are the major sink for oxygen in the cell, consuming it during ATP production.
Therefore, when environmental oxygen levels drop in the tumor, significant adaptation is …

Mitochondrial morphology, distribution and activity during oocyte development

D Bahety, E Böke, A Rodríguez-Nuevo - Trends in Endocrinology & …, 2024 - cell.com
Mitochondria have a crucial role in cellular function and exhibit remarkable plasticity,
adjusting both their structure and activity to meet the changing energy demands of a cell …

Mitochondrial Reactive Oxygen Species in Infection and Immunity

A Mukherjee, KK Ghosh, S Chakrabortty, B Gulyás… - Biomolecules, 2024 - mdpi.com
Reactive oxygen species (ROS) contain at least one oxygen atom and one or more unpaired
electrons and include singlet oxygen, superoxide anion radical, hydroxyl radical …

Mitochondrial calcium uniporter complex: Unveiling the interplay between its regulators and calcium homeostasis

J Guo, Y Wang, C Shi, D Zhang, Q Zhang, L Wang… - Cellular …, 2024 - Elsevier
The mitochondrial calcium uniporter complex (MCUc), serving as the specific channel for
calcium influx into the mitochondrial matrix, is integral to calcium homeostasis and cellular …

Transcriptome-wide analysis of the differences between MCF7 cells cultured in DMEM or αMEM

Y Jiao, H Zhao, L Lu, X Zhao, Y Wang, B Zheng - Plos one, 2024 - journals.plos.org
MCF7 cells have been used as an experimental model for breast cancer for decades.
Typically, a culture medium is designed to supply cells with the nutrients essential for their …

Mitochondrial metabolism regulation and epigenetics in hypoxia

M Laird, JC Ku, J Raiten, S Sriram, M Moore… - Frontiers in …, 2024 - frontiersin.org
The complex and dynamic interaction between cellular energy control and gene expression
modulation is shown by the intersection between mitochondrial metabolism and epigenetics …

[HTML][HTML] MiR-29a efficiently suppresses the generation of reactive oxygen species and α-synuclein in a cellular model of Parkinson's disease by potentially targeting …

YL Yang, TK Lin, YH Huang - European Journal of Pharmacology, 2024 - Elsevier
Abstract MicroRNA-29a (miR-29a) has been suggested to serve a potential protective
function against Parkinson's disease (PD); however, the exact molecular mechanisms …

[HTML][HTML] Semiconducting polymer dots for multifunctional integrated nanomedicine carriers

Z Zhang, C Yu, Y Wu, Z Wang, H Xu, Y Yan, Z Zhan… - Materials Today Bio, 2024 - Elsevier
The expansion applications of semiconducting polymer dots (Pdots) among optical
nanomaterial field have long posed a challenge for researchers, promoting their intelligent …

Research progress in mechanism of anticancer action of shikonin targeting reactive oxygen species

K Qi, J Li, Y Hu, Y Qiao, Y Mu - Frontiers in Pharmacology, 2024 - frontiersin.org
Excessive buildup of highly reactive molecules can occur due to the generation and
dysregulation of reactive oxygen species (ROS) and their associated signaling pathways …

Features of the Effect of Quercetin on Different Genotypes of Wheat under Hypoxia

LI Fedoreyeva, EM Lazareva… - International Journal of …, 2024 - mdpi.com
Hypoxia is one of the common abiotic stresses that negatively affects the development and
productivity of agricultural crops. Quercetin is used to protect plants from oxidative stress …