Operational feasibility of Plasmodium vivax radical cure with tafenoquine or primaquine following point-of-care, quantitative glucose-6-phosphate dehydrogenase …

M Brito, R Rufatto, F Murta, V Sampaio… - The Lancet Global …, 2024 - thelancet.com
Background To achieve malaria elimination, Brazil must implement Plasmodium vivax
radical cure. We aimed to investigate the operational feasibility of point-of-care, quantitative …

Putative contribution of 8-aminoquinolines to preventing recrudescence of malaria

MB Markus - Tropical Medicine and Infectious Disease, 2023 - mdpi.com
Enhanced therapeutic efficacy achieved in treating Plasmodium vivax malaria with an 8-
aminoquinoline (8-AQ) drug such as primaquine (PQ) together with a partner drug such as …

Plasmodium vivax merozoite-specific thrombospondin-related anonymous protein (PvMTRAP) interacts with human CD36, suggesting a novel ligand–receptor …

TS Nguyen, JH Park, TK Nguyen, TV Nguyen… - Parasites & …, 2023 - Springer
Abstract Background The Plasmodium vivax merozoite restrictively invades immature
erythrocytes, suggesting that its ligand (s) might interact with corresponding receptor (s) that …

Epidemiology of Plasmodium vivax in Duffy negatives and Duffy positives from community and health centre collections in Ethiopia

L Bradley, D Yewhalaw, E Hemming-Schroeder… - Malaria Journal, 2024 - Springer
Background Malaria remains a significant cause of morbidity and mortality in Ethiopia with
an estimated 3.8 million cases in 2021 and 61% of the population living in areas at risk of …

Evaluating the genetic diversity of the Plasmodium vivax siap2 locus: A promising candidate for an effective malaria vaccine?

SE Plata-Pineda, LX Cárdenas-Munévar… - Acta Tropica, 2024 - Elsevier
Malaria is the deadliest parasitic disease in the world. Traditional control measures have
become less effective; hence, there is a need to explore alternative strategies, such as …

Are pvcrt-o and pvmdr1 Gene Mutations Associated with Plasmodium vivax Chloroquine-Resistant Parasites?

R Abreu-Fernandes, NK Almeida-de-Oliveira… - Biomedicines, 2024 - mdpi.com
(1) Background: Malaria remains a significant global public health issue. Since parasites
quickly became resistant to most of the available antimalarial drugs, treatment effectiveness …

Expression, Purification, and Characterization of Plasmodium vivax Lactate Dehydrogenase from Bacteria without Codon Optimization

YJ Kim, JS Shin, KW Lee, HJ Eom, BG Jo… - International Journal of …, 2023 - mdpi.com
Plasmodium vivax is the most widespread cause of malaria, especially in subtropical and
temperate regions such as Asia-Pacific and America. P. vivax lactate dehydrogenase …

[HTML][HTML] Prevalence and characteristics of Plasmodium vivax Gametocytes in Duffy-positive and Duffy-negative populations across Ethiopia

E Little, TT Shenkutie, MT Negash… - The American Journal …, 2024 - ncbi.nlm.nih.gov
Plasmodium parasites replicate asexually in human hosts. The proportion of infections that
carries gametocytes is a proxy for human-to-mosquito transmissibility. It is unclear which …

Monitoring the density of Plasmodium spp. gametocytes in isolates from patient samples in the region of Porto Velho, Rondônia

L do Nascimento Martinez, DC Silva… - 3 Biotech, 2023 - Springer
Gametocytes are the forms of the malaria parasite that are essential for the continuation of
the transmission cycle to the vector Anopheles. This study aimed to evaluate the parasite …

[HTML][HTML] The effect of single low-dose primaquine treatment for uncomplicated Plasmodium falciparum malaria on hemoglobin levels in Ethiopia: a longitudinal cohort …

K Habtamu, H Getachew, A Abossie… - Research …, 2024 - ncbi.nlm.nih.gov
Background To interrupt residual malaria transmission and achieve successful elimination of
P. falciparum in low-transmission settings, the World Health Organization (WHO) …