[HTML][HTML] Recent advances in targeted drug delivery systems for resistant colorectal cancer
M Sharifi-Azad, M Fathi, WC Cho, A Barzegari… - Cancer Cell …, 2022 - Springer
Colorectal cancer (CRC) is one of the deadliest cancers in the world, the incidences and
morality rate are rising and poses an important threat to the public health. It is known that …
morality rate are rising and poses an important threat to the public health. It is known that …
[HTML][HTML] Disease modeling on tumor organoids implicates AURKA as a therapeutic target in liver metastatic colorectal cancer
SL Boos, LP Loevenich, S Vosberg, T Engleitner… - Cellular and Molecular …, 2022 - Elsevier
Background & Aims Patient-derived tumor organoids recapitulate the characteristics of
colorectal cancer (CRC) and provide an ideal platform for preclinical evaluation of …
colorectal cancer (CRC) and provide an ideal platform for preclinical evaluation of …
Differences in gene mutation profiles of colon cancer patients with or without a KRAS mutation
S Chang, Y Zhou, R Wu, X Ge, Y Pu - 2022 - researchsquare.com
RAS plays an important role in the carcinogenesis of colorectal epithelial cells, but RAS
mutations are only present, at most, in approximately 50% of patients. In order to compare …
mutations are only present, at most, in approximately 50% of patients. In order to compare …