Thermal processing has gained much interest in the pharmaceutical industry, particularly for
the enhancement of solubility, bioavailability, and dissolution of active pharmaceutical …

Objectives Supersaturating formulations hold great promise for delivery of poorly soluble
active pharmaceutical ingredients (APIs). To profit from supersaturating formulations …

The presence of different excipient types/brands in solid oral dosage forms may affect
product performance and drug bioavailability. Understanding the biopharmaceutical …

Supersaturation is a promising strategy to improve gastrointestinal absorption of poorly
water-soluble drugs. Supersaturation is a metastable state and therefore dissolved drugs …

The formulation of oral amorphous solid dispersions (ASD) includes the use of excipients to
improve physical stability and enhance bioavailability. Combinations of excipients (polymers …

The successful development of an amorphous form of a drug demands the use of process
conditions and materials that reduce their thermodynamic instability. For the first time, we …

Abstract In 2010, the Developability Classification System was proposed as an extension of
the Biopharmaceutics Classification System to align the classification system with the need …

Supersaturating formulations are widely used to improve the oral bioavailability of poorly
soluble drugs. However, supersaturated solutions are thermodynamically unstable and such …

Objective: The objective of this study was to prepare nanosuspension of a practical water
insoluble antiulcer drug which is lafutidine to enhance the solubility, dissolution rate with …

Objective: The aim of this study was to formulate a developed floating tablet of amlodipine
using different concentrations and types of hydrophilic and hydrophobic polymers to be …