Recent advances in nanoparticle applications in respiratory disorders: a review

ME Taghavizadeh Yazdi, M Qayoomian… - Frontiers in …, 2023 - frontiersin.org
Various nanoparticles are used in the discovery of new nanomedicine to overcome the
shortages of conventional drugs. Therefore, this article presents a comprehensive and up-to …

[HTML][HTML] Simulation-based approaches for drug delivery systems: navigating advancements, opportunities, and challenges

I Salahshoori, M Golriz, MAL Nobre, S Mahdavi… - Journal of Molecular …, 2023 - Elsevier
Efficient drug delivery systems (DDSs) play a pivotal role in ensuring pharmaceuticals'
targeted and effective administration. However, the intricate interplay between drug …

A review of non-invasive drug delivery through respiratory routes

YB Zhang, D Xu, L Bai, YM Zhou, H Zhang, YL Cui - Pharmaceutics, 2022 - mdpi.com
With rapid and non-invasive characteristics, the respiratory route of administration has
drawn significant attention compared with the limitations of conventional routes. Respiratory …

[HTML][HTML] Development of a new inhaled swellable microsphere system for the dual delivery of naringenin-loaded solid lipid nanoparticles and doxofylline for the …

A Pareek, R Kothari, A Pareek, Y Ratan… - European Journal of …, 2024 - Elsevier
This study developed a new dual delivery system of naringenin (NRG), a polyphenol, and
doxofylline (DOX), a xanthine derivative, as an inhaled microsphere system. In this system …

Preparation of Budesonide-Loaded Liposomal Nanoparticles for Pulmonary Delivery and Their Therapeutic Effect in OVA-Induced Asthma in Mice

X Zuo, Y Gu, X Guo, W Zheng, H Zheng… - International journal …, 2024 - Taylor & Francis
Purpose Inhaled corticosteroids, including budesonide (BUD), are widely employed for the
treatment of asthma. However, the frequent use of corticosteroids is associated with …

Recent advances in nanomaterials for asthma treatment

X Zuo, X Guo, Y Gu, H Zheng, Z Zhou, X Wang… - International Journal of …, 2022 - mdpi.com
Asthma is a chronic airway inflammatory disease with complex mechanisms, and these
patients often encounter difficulties in their treatment course due to the heterogeneity of the …

Therapeutic potential of controlled delivery systems in asthma: preclinical development of flavonoid-based treatments

SM Borghi, TH Zaninelli, JB Carra, OK Heintz… - Pharmaceutics, 2022 - mdpi.com
Asthma is a chronic disease with increasing prevalence and incidence, manifested by
allergic inflammatory reactions, and is life-threatening for patients with severe disease …

Tackling the cytokine storm using advanced drug delivery in allergic airway disease

VK Patel, S Vishwas, R Kumar, G De Rubis… - Journal of Drug Delivery …, 2023 - Elsevier
Asthma is one of the leading causes of mortality worldwide presenting a huge socio-
economic burden with rising morbidity and mortality rates. It is a chronic inflammatory airway …

Molecular dynamics study on the behavior and binding mechanism of target protein Transgelin-2 with its agonist TSG12 for anti-asthma drug discovery

L Wu, G Wang, L Zhou, M Mo, Y Shi, B Li, L Yin… - Computers in Biology …, 2023 - Elsevier
Abstract Transgelin-2 (TG2) is a novel promising therapeutic target for the treatment of
asthma as it plays an important role in relaxing airway smooth muscles and reducing …

[HTML][HTML] Inhalable nanomedicine for lung cancer treatment

S Zhang, R Li, T Jiang, Y Gao, K Zhong… - Smart Materials in …, 2024 - Elsevier
Lung cancer has surpassed other types of cancer to become the primary cause of cancer-
related deaths. Surgery stands as the foremost clinical treatment strategy available for …