This narrative mini-review summarizes current knowledge of the role of polyphenols in
health outcomes–and non-communicable diseases specifically–and discusses the …

Nuclear receptor coactivator 4 mediated ferritinophagy is an autophagic phenomenon that
specifically involves ferritin to release intracellular free iron. Ferritinophagy is implicated in …

Growing evidence has indicated that iron deposition is one of the key factors leading to
neuronal death in the neurodegenerative diseases. Ferritin is a hollow iron storage protein …

Parkinson's disease (PD) is one of the most common neurodegenerative movement
disorders worldwide. There are currently no cures or preventative treatments for PD …

Significance: Iron accumulation occurs in the central nervous system (CNS) in a variety of
neurological conditions as diverse as spinal cord injury, stroke, multiple sclerosis …

Ferroptosis is a novel type of cell death characterized by iron-dependent lipid peroxidation
that involves a variety of biological processes, such as iron metabolism, lipid metabolism …

The mitochondrion is an essential organelle important for the generation of ATP for cellular
function. This is especially critical for cells with high energy demands, such as neurons for …

Iron is a key element for mitochondrial function and homeostasis, which is also crucial for
maintaining the neuronal system, but too much iron promotes oxidative stress. A large body …

The incidence of neurological diseases, such as Parkinson's disease, Alzheimer's disease
and stroke, is increasing. An increasing number of studies have correlated these diseases …

Ferritinophagy is a type of autophagy mediated by nuclear receptor activator 4 (NCOA4),
which plays a role in inducing ferroptosis by regulating iron homeostasis and producing …