[HTML][HTML] Sex hormone fluctuation and increased female risk for depression and anxiety disorders: from clinical evidence to molecular mechanisms

M Kundakovic, D Rocks - Frontiers in neuroendocrinology, 2022 - Elsevier
Women are at twice the risk for anxiety and depression disorders as men are, although the
underlying biological factors and mechanisms are largely unknown. In this review, we …

Sex differences in depression: Insights from clinical and preclinical studies

RS Eid, AR Gobinath, LAM Galea - Progress in neurobiology, 2019 - Elsevier
Depression represents a global mental health concern, and disproportionally affects women
as they are twice more likely to be diagnosed than men. In this review, we provide a …

[HTML][HTML] The role of placental hormones in mediating maternal adaptations to support pregnancy and lactation

T Napso, HEJ Yong, J Lopez-Tello… - Frontiers in …, 2018 - frontiersin.org
During pregnancy, the mother must adapt her body systems to support nutrient and oxygen
supply for growth of the baby in utero and during the subsequent lactation. These include …

[HTML][HTML] Birth as a neuro-psycho-social event: An integrative model of maternal experiences and their relation to neurohormonal events during childbirth

I Olza, K Uvnas-Moberg, A Ekström-Bergström… - Plos one, 2020 - journals.plos.org
Background Psychological aspects of labor and birth have received little attention within
maternity care service planning or clinical practice. The aim of this paper is to propose a …

Stress, sex hormones, inflammation, and major depressive disorder: Extending Social Signal Transduction Theory of Depression to account for sex differences in …

GM Slavich, J Sacher - Psychopharmacology, 2019 - Springer
Abstract Social Signal Transduction Theory of Depression is a biologically plausible, multi-
level theory that describes neural, physiologic, molecular, and genomic mechanisms that …

[HTML][HTML] Sex differences in the human brain: a roadmap for more careful analysis and interpretation of a biological reality

AR DeCasien, E Guma, S Liu, A Raznahan - Biology of Sex Differences, 2022 - Springer
The presence, magnitude, and significance of sex differences in the human brain are hotly
debated topics in the scientific community and popular media. This debate is largely fueled …

Sex differences in hippocampal cognition and neurogenesis

S Yagi, LAM Galea - Neuropsychopharmacology, 2019 - nature.com
Sex differences are reported in hippocampal plasticity, cognition, and in a number of
disorders that target the integrity of the hippocampus. For example, meta-analyses reveal …

[HTML][HTML] Menopause impacts human brain structure, connectivity, energy metabolism, and amyloid-beta deposition

L Mosconi, V Berti, J Dyke, E Schelbaum, S Jett… - Scientific reports, 2021 - nature.com
All women undergo the menopause transition (MT), a neuro-endocrinological process that
impacts aging trajectories of multiple organ systems including brain. The MT occurs over …

[HTML][HTML] Mapping the effects of pregnancy on resting state brain activity, white matter microstructure, neural metabolite concentrations and grey matter architecture

E Hoekzema, H van Steenbergen, M Straathof… - Nature …, 2022 - nature.com
While animal studies have demonstrated a unique reproduction-related neuroplasticity, little
is known on the effects of pregnancy on the human brain. Here we investigated whether …

[HTML][HTML] Matrescence: lifetime impact of motherhood on cognition and the brain

ER Orchard, HJV Rutherford, AJ Holmes… - Trends in cognitive …, 2023 - cell.com
Profound environmental, hormonal, and neurobiological changes mark the transition to
motherhood as a major biosocial life event. Despite the ubiquity of motherhood, the …