Cerebrovascular disease is the second most common cause of acquired cognitive
impairment and dementia and contributes to cognitive decline in the neurodegenerative …

Mild cognitive impairment (MCI) is a recently described syndrome that is currently thought of
as a transition phase between healthy cognitive ageing and dementia. Although this notion …

Background Mild cognitive impairment is increasingly recognized as an important public
health problem associated with increased risk of developing dementia. Annual conversion …

Background Higher adherence to the Mediterranean diet (MeDi) may protect from Alzheimer
disease (AD), but its association with mild cognitive impairment (MCI) has not been …

To determine the size of the impairment across different cognitive domains in preclinical
Alzheimer's disease (AD), a meta-analysis based on 47 studies involving 9,097 controls and …

Objectives: Older people commonly present with memory loss although on assessment are
not found to have a full dementia complex. Previous studies have suggested however that …

As identified in previously published articles, including those published in this issue, the
detection of early cognitive impairment among older adult populations is worthy of …

Introduction Cerebral small vessel disease is increasingly linked to dementia. Methods We
systematically searched Medline, Embase, and Cochrane databases for prospective …

Objective: To analyze the extent and spatial distribution of white matter hyperintensities
(WMH) in brain regions from cognitively normal older individuals (CN) and patients with mild …

The literature on cognitive markers in preclinical AD is reviewed. The findings demonstrate
that impairment in multiple cognitive domains is typically observed several years before …