Background Aquaporin (AQP) water channels are best known as passive transporters of
water that are vital for water homeostasis. Scope of review AQP knockout studies in whole …

Lens, an avascular organ involved in light transmission, contains an internal micro-
circulatory system coupling ions to fluid movement, thus providing nutrients to internal lens …

Maintenance of proper biomechanics of the eye lens is important for its structural integrity
and for the process of accommodation to focus near and far objects. Several studies have …

Purpose Aquaporins (AQPs) play a significant role in the movement of water across the
plasma membrane. In the eye, the cornea and lens are avascular with unique …

Abstract Aquaporin 0 (AQP0) performs dual functions in the lens fiber cells, as a water pore
and as a cell-to-cell adhesion molecule. Mutations in AQP0 cause severe lens cataract in …

With age, long-lived proteins in the human body deteriorate, which can have consequences
both for aging and disease. The aging process is often associated with the formation of …

Abstract Aquaporin 0 (AQP0) is a transmembrane channel that constitutes∼ 45% of the total
membrane protein of the fiber cells in mammalian lens. It is critical for lens transparency and …

Aquaporins (AQPs), ordinarily regarded as water channels, have recently been shown to
participate in other cellular functions such as cell-to-cell adhesion, cell migration, cell …

Aquaporins (AQPs) can be revisited from a distinct and complementary perspective: the
outcome from analyzing them from both plant and animal studies.(1) The approach in the …

The scope of this investigation was to understand the role of aquaporin 5 (AQP5) for
maintaining lens transparency and homeostasis. Studies were conducted using lenses of …