Host defense peptide mimicking antimicrobial amino acid polymers and beyond: Design, synthesis and biomedical applications

Y Wu, K Chen, J Wang, M Chen, Y Chen, Y She… - Progress in Polymer …, 2023 - Elsevier
Microbial infections endanger human health and life. Conventional antibiotics has saved
countless human lives, however, is seriously challenged by the quick emergence of …

Beyond nylon 6: Polyamides via ring opening polymerization of designer lactam monomers for biomedical applications

M Varghese, MW Grinstaff - Chemical Society Reviews, 2022 - pubs.rsc.org
Ring opening polymerization (ROP) of lactams is a highly efficient and versatile method to
synthesize polyamides. Within the last ten years, significant advances in polymerization …

[HTML][HTML] Advances in the antimicrobial treatment of osteomyelitis

C Zhong, Y Wu, H Lin, R Liu - Composites Part B: Engineering, 2023 - Elsevier
Osteomyelitis is a major complication of orthopedic diseases with high recurrence and
morbidity, along with long hospital stays and high medical costs. The conventional treatment …

Peptide-mimicking poly (2-oxazoline) s possessing potent antifungal activity and BBB penetrating property to treat invasive infections and meningitis

W Jiang, M Zhou, S Chen, J Xie, M Chen… - Journal of the …, 2023 - ACS Publications
Invasive fungal infections, including meningitis, cause a high mortality rate due to few
available antifungal drugs and frequently associated side effects and quick emergence of …

An effective strategy to develop potent and selective antifungal agents from cell penetrating peptides in tackling drug-resistant invasive fungal infections

Y Wu, W Jiang, Z Cong, K Chen, Y She… - Journal of Medicinal …, 2022 - ACS Publications
The high mortality rate of invasive fungal infections and quick emergence of drug-resistant
fungal pathogens urgently call for potent antifungal agents. Inspired by the cell penetrating …

Ultra-transparent, hard and antibacterial coating with pendent quaternary pyridine salt

Y Cao, Z Yang, J Ou, L Jiang, G Chu, Y Wang… - Progress in Organic …, 2023 - Elsevier
Pathogenic microbes are ubiquitous, and they can proliferate quickly on wood surface under
the suitable conditions to pose a huge hidden threat to public health security and safety. To …

Boosting stability and therapeutic potential of proteolysis-resistant antimicrobial peptides by end-tagging β-naphthylalanine

S He, Z Yang, X Li, H Wu, L Zhang, A Shan, J Wang - Acta Biomaterialia, 2023 - Elsevier
Recently, much emphasis has been placed on solving the intrinsic defects of antimicrobial
peptides (AMPs), especially their susceptibility to protease digestion for the systemic …

[HTML][HTML] A synthetic peptide mimic kills Candida albicans and synergistically prevents infection

S Schaefer, R Vij, JL Sprague, S Austermeier… - Nature …, 2024 - nature.com
More than two million people worldwide are affected by life-threatening, invasive fungal
infections annually. Candida species are the most common cause of nosocomial, invasive …

Dual coordination between stereochemistry and cations endows polyethylene terephthalate fabrics with diversiform antimicrobial abilities for attack and defense

P Zhang, X Chen, F Bu, C Chen, L Huang… - … Applied Materials & …, 2023 - ACS Publications
Modification of fabrics by stereochemical antiadhesion strategies is an emerging approach
to antimicrobial fabric finishing. However, a purely antiadhesive fabric cannot avoid the …

Traditional Herb (Moxa) Modified Zinc Oxide Nanosheets for Quick, Efficient and High Tissue Penetration Therapy of Fungal Infection

Z Weng, Q Wei, C Ye, Y Xu, J Gao, W Zhang, L Liu… - ACS …, 2024 - ACS Publications
Fungal infection possesses the characteristics of high invasion depth and easy formation of
a biofilm under the skin, which greatly hinders the treatment process. Here, traditional …