Early-onset colorectal cancer: current insights

F Ullah, AB Pillai, N Omar, D Dima, S Harichand - Cancers, 2023 - mdpi.com
Simple Summary Early-onset colorectal cancer is increasing in incidence in the United
States, and it is expected to more than double in the next 10 years. There are many risk …

Obesity and early-onset colorectal cancer risk: emerging clinical evidence and biological mechanisms

P Xu, Z Tao, H Yang, C Zhang - Frontiers in Oncology, 2024 - frontiersin.org
Early-onset colorectal cancer (EOCRC) is indicated as a global burden. EOCRC The
disease is associated with specific molecular and clinical features. As Obesity is a well …

Early Age of Onset Is an Independent Predictor for a Worse Response to Neoadjuvant Therapies in Sporadic Rectal Cancer Patients

C Foppa, A Maroli, A Luberto, C La Raja, P Spaggiari… - Cancers, 2023 - mdpi.com
Simple Summary Early-onset rectal cancer (EORC) patients are more likely to undergo
neoadjuvant therapies due to the advanced stage of cancer at diagnosis. The response to …

Molecular profiling of pediatric and young adult colorectal cancer reveals a distinct genomic landscapes and potential therapeutic avenues

A Busico, P Gasparini, E Rausa, L Cattaneo, F Bozzi… - Scientific Reports, 2024 - nature.com
Colorectal cancer (CRC) is a global health concern, and the incidence of early onset (EO)
CRC, has an upward trend. This study delves into the genomic landscape of EO-CRC …

Survival Analysis of Metastatic Early-Onset Colorectal Cancer Compared to Metastatic Average-Onset Colorectal Cancer: A SEER Database Analysis

A Jeri-Yabar, L Vittini-Hernandez, S Prado-Nuñez… - Cancers, 2024 - mdpi.com
Simple Summary Over the last decade, early-onset colorectal cancer incidence has
continued to increase. The disparities in outcomes and overall survival (OS) between early …

[HTML][HTML] Early onset metastatic colorectal cancer in Australia

A Jalali, S Smith, G Kim, H Wong, M Lee… - Cancer Treatment and …, 2024 - Elsevier
Background Colorectal cancer (CRC) incidence and mortality rates have been increasing
among young patients (YP), for uncertain reasons. It is unclear whether YP have a distinct …

Risk factors, histopathological landscape, biomarkers, treatment patterns and survival of early‐onset colorectal cancer: A narrative review

C Garrett, D Steffens, S Ackland… - Asia‐Pacific Journal …, 2024 - Wiley Online Library
Early‐onset colorectal cancer (EOCRC) incidence has increased in most Western countries
over the last decade, with Australia at the forefront. Recent literature has thus focused on …

Early versus Late Onset Colorectal Cancer: Pathological Distinctions and Optimal Screening Age Determination in a Decade-Long Study

J Song, T Han, L Qian, J Zhu, Y Qiao, S Liu, P Yu… - 2024 - researchsquare.com
Abstract Background and Aim: The incidence of Early-Onset Colorectal Cancer (EOCRC) is
increasing. However, the prognosis of EOCRC compared to Late-Onset Colorectal Cancer …