[HTML][HTML] Advancements and applications of single-cell multi-omics techniques in cancer research: Unveiling heterogeneity and paving the way for precision …

A Liang, Y Kong, Z Chen, Y Qiu, Y Wu, X Zhu… - … and Biophysics Reports, 2024 - Elsevier
Single-cell multi-omics technologies have revolutionized cancer research by allowing us to
examine individual cells at a molecular level. Unlike traditional bulk omics approaches …

[HTML][HTML] A global view of aging and Alzheimer's pathogenesis-associated cell population dynamics and molecular signatures in human and mouse brains

A Sziraki, Z Lu, J Lee, G Banyai, S Anderson… - Nature Genetics, 2023 - nature.com
Conventional methods fall short in unraveling the dynamics of rare cell types related to
aging and diseases. Here we introduce EasySci, an advanced single-cell combinatorial …

Adult Hippocampal Neurogenesis in the Human Brain: Updates, Challenges, and Perspectives

S Simard, N Matosin, N Mechawar - The Neuroscientist, 2024 - journals.sagepub.com
The existence of neurogenesis in the adult human hippocampus has been under
considerable debate within the past three decades due to the diverging conclusions …

[HTML][HTML] Dentate gyrus is needed for memory retrieval

A Carretero-Guillén, M Treviño… - Molecular …, 2024 - nature.com
The hippocampus is crucial for acquiring and retrieving episodic and contextual memories.
In previous studies, the inactivation of dentate gyrus (DG) neurons by chemogenetic-and …

Evolution of plant cell-type-specific cis-regulatory elements

H Yan, JP Mendieta, X Zhang, AP Marand, Y Liang… - bioRxiv, 2024 - biorxiv.org
Cis-regulatory elements (CREs) are critical in coordinating the regulation of gene
expression. Understanding how CREs evolve represents a challenging endeavor. Here, we …