Метаанализ исследований, посвященных изучению конкордантности мутационного статуса генов между первичной опухолью и метастазами рака толстой …

МЮ Федянин, АА Трякин, ИА Покатаев… - Тазовая хирургия и …, 2017 - cyberleninka.ru
Введение. В последние годы появился ряд исследований, демонстрирующих высокую
гетерогенность опухолей, в том числе и рака толстой кишки. Цель исследования …

循环肿瘤细胞单细胞测序--液体活检的新视角

赵丽娜, 赵晓航 - 生命科学, 2018 - cqvip.com
循环肿瘤细胞是实体肿瘤原发灶或转移灶侵袭, 脱落进入外周血的, 具有高活力,
高转移潜能的肿瘤细胞. 由于肿瘤存在异质性, 导致肿瘤组织高通量测序分析难以发现低丰度 …

[HTML][HTML] KRAS 基因的突变状态对EGFR 单抗治疗结直肠癌的影响

张惠锋, 王昆华 - 世界华人消化杂志, 2016 - wjgnet.com
结直肠癌(colorectal cancer, CRC) 是常见的恶性肿瘤之一, 随着我国经济发展和人民生活水平
的不断提高, 生活方式及饮食结构的改变, CRC 的发病率呈逐年上升趋势. CRC …

[PDF][PDF] Role of single nucleotide polymorphisms of KRAS and BRAF genes in susceptibility for papillary thyroid carcinoma and patients prognosis

Z Yang, J Huang, W Jing - Int J Clin Exp Pathol, 2016 - e-century.us
Genetic variations within oncogene are frequently detected in many kinds of malignancies,
including papillary thyroid carcinoma (PTC). Rs712 within 3'-untranslated region (UTR) of …

High mutational concordance between primary colorectal tumors and associated pulmonary metastases

EM Corsini, SS Datar, KG Mitchell… - Journal of surgical …, 2020 - Wiley Online Library
Abstract Background and Objectives Precision medicine has altered the management of
colorectal cancer (CRC). However, the concordance of mutational findings between primary …

Left versus right: does location matter for refractory metastatic colorectal cancer patients in phase 1 clinical trials?

SP Arora, NS Ketchum, J Michalek, J Gelfond… - Journal of …, 2018 - Springer
Purpose Location of the primary tumor is prognostic and predictive of efficacy with VEGF-
inhibitors (I) versus EGFR-I given first-line to metastatic colorectal cancer (mCRC) patients …

[PDF][PDF] ZNS-Metastasen beim kolorektalen Karzinom: Evaluation von Krankheitsverlauf, Metastasierungsmuster, Überlebenszeiten und Prognosefaktoren

J Thurmaier - 2021 - scholar.archive.org
ZNS-Metastasen beim kolorektalen Karzinom - Evaluation von Krankheitsverlauf,
Metastasierungsmuster, Überlebenszeiten und Progn Page 1 Aus der medizinischen Klinik und …

[PDF][PDF] Radiogenomics in Colorectal Cancer. Cancers 2021, 13, 973

B Badic, F Tixier, C Cheze Le Rest, M Hatt, D Visvikis - 2021 - pdfs.semanticscholar.org
The steady improvement of high-throughput technologies greatly facilitates the
implementation of personalized precision medicine. Characterization of tumor heterogeneity …

二代测序技术在结直肠癌基因组测序中应用的研究进展

鲁有望, 王昆华 - 吉林大学学报: 医学版, 2016 - cqvip.com
二代测序技术在结直肠癌基因组测序中应用的研究进展-[维普官方网站]-www.cqvip.com-维普网 
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Multiplexed dosing assays by digitally definable hydrogel volumes

A Faralli, F Melander, EKU Larsen… - Advanced …, 2016 - Wiley Online Library
Stable and low‐cost multiplexed drug sensitivity assays using small volumes of cells or
tissue are in demand for personalized medicine, including patient‐specific combination …