Multifunctional approaches utilizing polymeric micelles to circumvent multidrug resistant tumors
SS Kesharwani, S Kaur, H Tummala… - Colloids and Surfaces B …, 2019 - Elsevier
The concerns impeding the success of chemotherapy in cancer is descending efficacy of
drugs due to the development of multiple drug resistance (MDR). The current efforts …
drugs due to the development of multiple drug resistance (MDR). The current efforts …
[HTML][HTML] Quality by design based formulation study of meloxicam-loaded polymeric micelles for intranasal administration
Our study aimed to develop an “ex tempore” reconstitutable, viscosity enhancer-and
preservative-free meloxicam (MEL)-loaded polymeric micelle formulation, via Quality by …
preservative-free meloxicam (MEL)-loaded polymeric micelle formulation, via Quality by …
The landscape of nanoparticle-based siRNA delivery and therapeutic development
Five small interfering RNA (siRNA)-based therapeutics have been approved by the Food
and Drug Administration (FDA), namely patisiran, givosiran, lumasiran, inclisiran, and …
and Drug Administration (FDA), namely patisiran, givosiran, lumasiran, inclisiran, and …
Recent progress of polymeric nanogels for gene delivery
R Kandil, OM Merkel - Current opinion in colloid & interface science, 2019 - Elsevier
With its nearly unrestricted possibilities, gene therapy attracts more and more significance in
modern-day research. The only issue still seeming to hold back its clinical success is the …
modern-day research. The only issue still seeming to hold back its clinical success is the …
Spatio-temporal control strategy of drug delivery systems based nano structures
N Rahoui, B Jiang, N Taloub, YD Huang - Journal of Controlled Release, 2017 - Elsevier
The drug instability, toxicity and the barrier to the target area necessitate a suitable drug
delivery system with an external or internal control of the release. Spatio-temporal control …
delivery system with an external or internal control of the release. Spatio-temporal control …
Nanoparticle formulations to enhance tumor targeting of poorly soluble polyphenols with potential anticancer properties
Polyphenols have been extensively studied for their relevant anticancer activity. Quite often
however their instability, extensive metabolization, low bioavailability and poor solubility limit …
however their instability, extensive metabolization, low bioavailability and poor solubility limit …
Ketoconazole encapsulated in chitosan-gellan gum nanocomplexes exhibits prolonged antifungal activity
The objective of the present study was to prepare ketoconazole loaded chitosan-gellan gum
(CSGG) nanoparticles and to evaluate them for antifungal activity against Aspergillus niger …
(CSGG) nanoparticles and to evaluate them for antifungal activity against Aspergillus niger …
Block copolymer prodrugs: Synthesis, self‐assembly, and applications for cancer therapy
D Dutta, W Ke, L Xi, W Yin, M Zhou… - Wiley Interdisciplinary …, 2020 - Wiley Online Library
Block copolymer prodrugs (BCPs) have emerged as one of the most promising anticancer
drug delivery strategies, which can self‐assemble into nanoparticles with optimal …
drug delivery strategies, which can self‐assemble into nanoparticles with optimal …
Synthesis and characterization of stimuli responsive micelles from chitosan, starch, and alginate based on graft copolymers with polylactide-poly (methacrylic acid) …
A Pourjavadi, FB Kashani, M Doroudian… - International Journal of …, 2023 - Elsevier
The primary objective of this paper is to serve as a comprehensive study on the synthesis of
stimulus-sensitive micelles based on polysaccharides. In pursuit of this goal …
stimulus-sensitive micelles based on polysaccharides. In pursuit of this goal …
Soluplus® as a solubilizing excipient for poorly water-soluble drugs: recent advances in formulation strategies and pharmaceutical product features
Since the emergence of Soluplus®(SOL) as a commercial graft copolymer, several
publications have been issued on its promising potential as a solubilizing excipient that …
publications have been issued on its promising potential as a solubilizing excipient that …