Gender and sex are key determinants in osteoarthritis not only confounding variables. A systematic review of clinical data

M Tschon, D Contartese, S Pagani, V Borsari… - Journal of clinical …, 2021 - mdpi.com
Many risk factors for osteoarthritis (OA) have been noted, while gender/sex differences have
been understated. The work aimed to systematically review literature investigating as …

[HTML][HTML] Association of Klotho with physical performance and frailty in middle-aged and older adults: A systematic review

F Veronesi, V Borsari, A Cherubini, M Fini - Experimental Gerontology, 2021 - Elsevier
Ageing is an inevitable process of physical deterioration that impairs functional autonomy
and quality of life, becoming a public health issue. Since the percentage of people over 60 …

Clinical trials for neuroregenerative therapies for spinal cord injury: What have we learnt so far?

R Wong, N Hejrati, MG Fehlings - Expert Review of …, 2023 - Taylor & Francis
Introduction There remains a lack of effective regenerative therapies to treat traumatic spinal
cord injury (SCI). On a global level, patients living with SCI, their families, and the healthcare …

[HTML][HTML] Association Between Neutrophil–Lymphocyte Ratio and Frailty: The Chinese Longitudinal Healthy Longevity Survey

W Xu, Y Liang, Z Lin - Frontiers in Medicine, 2022 - frontiersin.org
Background: Inflammation has been reported to play an important role in frailty syndrome.
The neutrophil–lymphocyte ratio (NLR) has recently emerged as an informative marker for …

Frailty and sarcopenia: impact on outcomes following elective degenerative lumbar spine surgery

S Chotai, R Gupta, JS Pennings, AM Hymel, KR Archer… - Spine, 2022 - journals.lww.com
Study Design. This is a retrospective review of prospectively collected data. Objective. The
aim was to evaluate the impact of frailty and sarcopenia on outcomes after lumbar spine …

Frailty assessment and prehabilitation before complex spine surgery in patients with degenerative spine disease: a narrative review

B Mohamed, R Ramachandran, F Rabai… - Journal of …, 2023 - journals.lww.com
Degenerative spine disease increases in prevalence and may become debilitating as
people age. Complex spine surgery may offer relief but becomes riskier with age. Efforts to …

[HTML][HTML] Hospital frailty risk score predicts worse outcomes in patients with chronic pancreatitis

A Sohal, H Chaudhry, I Kohli, G Gupta… - Annals of …, 2023 - ncbi.nlm.nih.gov
Background Chronic pancreatitis (CP) is a pathological fibroinflammatory response to
persistent inflammation or stress to the pancreas. The effect of frailty on outcomes in patients …

A comparative analysis of frailty, disability, and sarcopenia with patient characteristics and outcomes in adult spinal deformity surgery

OS Akbik, N Al-Adli, MN Pernik, WH Hicks… - Global spine …, 2023 - journals.sagepub.com
Study Design Retrospective case series study. Objectives This study aims to compare
preoperative indices, including the modified frailty index-11 (mFI-11), modified frailty index-5 …

The modified 5-item frailty index determines the length of hospital stay and accompanies with mortality rate in patients with bone and implant-associated infections …

F Erne, V Wallmeier, C Ihle, BJ Braun, S Ehnert… - Injury, 2023 - Elsevier
Background Bone and implant-associated infections are severe complications after trauma
and orthopedic surgery. The modified 5-item frailty index (mFI-5) is an easily applicable …

Geriatric spine fractures–Demography, changing trends, challenges and special considerations: A narrative review

A Sunder, HS Chhabra, A Aryal - Journal of clinical orthopaedics and …, 2023 - Elsevier
The aim of this manuscript was to summarize the demography and changing trends of
geriatric spinal injuries and to enumerate the challenges and special considerations in the …