A defining feature of sleep is reduced responsiveness to external stimuli, but the
mechanisms mediating sensory-evoked arousal remain unclear. We hypothesized that …

Functional magnetic resonance imaging (fMRI) noninvasively measures human brain
activity at millimeter resolution. Scientists use different approaches to take advantage of the …

Neocortical activity is permeated with endogenously generated fluctuations, but how these
dynamics affect goal-directed behavior remains a mystery. We found that ensemble neural …

Neuromodulation underlies many behavioral states and has been extensively studied in
small circuits. This has allowed the systematic exploration of how neuromodulatory …

Neurofeedback (NFB) is emerging as a promising technique that enables self-regulation of
ongoing brain oscillations. However, despite a rise in empirical evidence attesting to its …

Transient episodes of brain oscillations are a common feature of both the waking and the
sleeping brain. Sleep spindles represent a prominent example of a poorly understood …

Noradrenergic and cholinergic systems are among the most vulnerable brain systems in
neuropsychiatric diseases of ageing, including Alzheimer's disease, Parkinson's disease …

Long-range corticocortical communication may have important roles in context-dependent
sensory processing, yet we know very little about how these pathways influence their target …

The tools of weakly coupled phase oscillator theory have had a profound impact on the
neuroscience community, providing insight into a variety of network behaviours ranging from …

Background Neural responses in visual cortex depend not only on sensory input but also on
behavioral context. One such context is locomotion, which modulates single-neuron activity …