Oligodendrocyte precursor cells (OPCs) generate oligodendrocytes, contributing to
myelination and myelin repair. OPCs contact axons and respond to neuronal activity, but …

Neuroscience studies are often carried out in animal models for the purpose of
understanding specific aspects of the human condition. However, the translation of findings …

Slow oscillations have been suggested as the default emergent activity of the cortical
network. This is a low complexity state that integrates neuronal, synaptic, and connectivity …

Decisions are often made by accumulating ambiguous evidence over time. The brain's
arousal systems are activated during such decisions. In previous work in humans, we found …

Behavior relies on the distributed and coordinated activity of neural populations. Population
activity can be measured using multi-neuron recordings and neuroimaging. Neural …

Fluctuations in arousal, controlled by subcortical neuromodulatory systems, continuously
shape cortical state, with profound consequences for information processing. Yet, how …

The neocortex is densely innervated by basal forebrain (BF) cholinergic neurons. Long-
range axons of cholinergic neurons regulate higher-order cognitive function and dysfunction …

The basal forebrain cholinergic system is widely assumed to control cortical functions via
non-synaptic transmission of a single neurotransmitter. Yet, we find that mouse hippocampal …

Neural mechanisms that detect changes in the auditory environment appear to rely on
processes that predict sensory state. Here we propose that in tinnitus there is a disparity …

Our brains have evolved the ability to configure and adapt their processing states to match
the unique challenges of acting and learning in diverse environments and behavioral …