[HTML][HTML] Current therapies in clinical trials of Parkinson's disease: A 2021 update

EM Prasad, SY Hung - Pharmaceuticals, 2021 - mdpi.com
Parkinson's disease (PD) is a progressive neurodegenerative disorder that currently has no
cure, but treatments are available to improve PD symptoms and maintain quality of life. In …

[HTML][HTML] The rise of SARS-CoV-2 variants and the role of convalescent plasma therapy for management of infections

M Moubarak, KI Kasozi, HF Hetta, HM Shaheen, A Rauf… - Life, 2021 - mdpi.com
Novel therapies for the treatment of COVID-19 are continuing to emerge as the SARS-Cov-2
pandemic progresses. PCR remains the standard benchmark for initial diagnosis of COVID …

[HTML][HTML] Transfusion transmissible infections in blood donors in the Province of Bié, Angola, during a 15-year follow-up, imply the need for pathogen reduction …

LB Peliganga, VM Mello, PSF de Sousa, MAP Horta… - Pathogens, 2021 - mdpi.com
Transfusion transmissible infections (TTIs), caused by hepatitis B virus (HBV), human
immunode-ficiency virus (HIV), hepatitis C virus (HCV), and syphilis, have a high global …

Impact of pathogen reduction methods on immunological properties of the COVID‐19 convalescent plasma

AI Kostin, MN Lundgren, AY Bulanov… - Vox …, 2021 - Wiley Online Library
Background and objectives COVID‐19 convalescent plasma is an experimental treatment
against SARS‐CoV‐2. The aim of this study is to assess the impact of different pathogen …

Stepwise options for preparing therapeutic plasma proteins from domestic plasma in low‐and middle‐income countries

T Burnouf, J Epstein, JC Faber, WM Smid… - Vox …, 2024 - Wiley Online Library
Industrial plasma fractionation, a complex and highly regulated technology, remains largely
inaccessible to many low‐and middle‐income countries (LMICs). This, combined with the …

[HTML][HTML] Rare congenital bleeding disorders

M Franchini, G Marano, S Pupella… - Annals of …, 2018 - ncbi.nlm.nih.gov
The rare congenital bleeding disorders are a heterogeneous group of diseases which
include deficiencies of fibrinogen, prothrombin and factors V, V+ VIII, VII, X, XI and XIII. They …

[HTML][HTML] The Preclinical Validation of 405 nm Light Parasiticidal Efficacy on Leishmania donovani in Ex Vivo Platelets in a Rag2−/− Mouse Model

PR Kaldhone, N Azodi, HL Markle, N Dahiya, C Stewart… - Microorganisms, 2024 - mdpi.com
Violet–blue light of 405 nm in the visible spectrum at a dose of 270 J/cm2 alone has been
shown to be an effective microbicidal tool for inactivating several bacteria, HIV-1, and …

Pathogen reduction: the state of the science in 2019

EA Gehrie, SJ Rutter, EL Snyder - Hematology/Oncology …, 2019 - hemonc.theclinics.com
Efforts and processes to ensure safety of the blood supply are critical and widespread in
transfusion medicine. Positive patient identification for type and screens and crossmatches …

Efficient Inactivation of Enveloped Viruses Using a Nanoparticle-Based Photodynamic Method

G Zhang, L Kuang, Y Liu, C Jiang, R Yang… - ACS Applied Nano …, 2023 - ACS Publications
Enveloped viruses pose a critical health threat to human beings. Photodynamic inactivation
shows promise but requires a relatively long time of irradiation or a high power intensity …

Attitudes and perceptions among men having sex with men towards a new non‐deferral blood donation policy in Israel

I Levy, L Olmer, Y Livnat, R Shalhavi, O Hizki… - Vox …, 2019 - Wiley Online Library
Background In June 2017, Israel lifted the ban on blood donations from men who have sex
with men (MSM) and accepts donations if 12 months have passed since the last sexual …