[HTML][HTML] Mechanisms of oxidized LDL-mediated endothelial dysfunction and its consequences for the development of atherosclerosis

H Jiang, Y Zhou, SM Nabavi, A Sahebkar… - Frontiers in …, 2022 - frontiersin.org
Atherosclerosis is the immuno-metabolic disease involving chronic inflammation, oxidative
stress, epigenetics, and metabolic dysfunction. There is compelling evidence suggesting …

[HTML][HTML] Regulatory mechanism of miR-20a-5p expression in Cancer

W Huang, X Wu, S Xiang, M Qiao, X Cen, X Pan… - Cell Death …, 2022 - nature.com
MicroRNAs (miRNAs) are non-coding single-stranded RNA molecules encoded by
endogenous genes with a length of about 22 nucleotides. The dysregulation of miRNAs has …

A circular RNA, circUSP36, accelerates endothelial cell dysfunction in atherosclerosis by adsorbing miR-637 to enhance WNT4 expression

J Huang, X Tang, J Wang, J Liu, P Chen, Y Sun - Bioengineered, 2021 - Taylor & Francis
Atherosclerosis is a fatal disorder that is fundamental to various cardiovascular diseases
and severely threatens people's health worldwide. Several studies have demonstrated the …

CircRNA–miRNA interactions in atherogenesis

KL Tong, KE Tan, YY Lim, XY Tien, PF Wong - Molecular and cellular …, 2022 - Springer
Atherosclerosis is the major cause of coronary artery disease (CAD) which includes
unstable angina, myocardial infarction, and heart failure. The onset of atherogenesis, a …

Role and mechanism of circular RNA circ_0050486 in regulating oxidized low-density lipoprotein-induced injury in endothelial cells

P Zhang, W Wang, M Li - Clinical Hemorheology and …, 2022 - content.iospress.com
BACKGROUND: Dysfunction of endothelial cells in the arterial vasculature is an essential
contributor to the pathogenesis of atherosclerosis. Circular RNAs (circRNAs) exert important …

Circ_HECW2 regulates ox-LDL-induced dysfunction of cardiovascular endothelial cells by miR-942-5p/TLR4 axis

W Wei, M Tang, Q Wang, X Li - Clinical Hemorheology and …, 2022 - content.iospress.com
BACKGROUND: Coronary artery disease (CAD) is a common coronary artery disease. The
functional mechanism of circular RNA (circRNA) HECT, C2 and WW domain containing E3 …

Circ_0091822 aggravates ox-LDL-induced endothelial cell injury through targeting the miR-661/RAB22A axis

L Zhu, P Zhao, X Meng, H Jin… - Clinical Hemorheology …, 2023 - content.iospress.com
BACKGROUND: Endothelial dysfunction is considered to be an important factor in the
pathogenesis of atherosclerosis. Circular RNAs (circRNAs) have been confirmed to …

CircCHMP5 contributes to Ox-LDL-induced endothelial cell injury through the regulation of MiR-532-5p/ROCK2 axis

X Li, X Kang, Y Di, S Sun, L Yang, B Wang… - Cardiovascular drugs and …, 2023 - Springer
Background Aberrant expression of circular RNA (circRNA) has been demonstrated to be
related to atherosclerosis (AS) formation. However, the mechanism of circCHMP5 (also …

[HTML][HTML] Emerging Roles of extracellular vesicle-delivered circular RNAs in atherosclerosis

C Wen, B Li, L Nie, L Mao, Y Xia - Frontiers in Cell and …, 2022 - frontiersin.org
Atherosclerosis (AS) is universally defined as chronic vascular inflammation induced by
dyslipidaemia, obesity, hypertension, diabetes and other risk factors. Extracellular vesicles …

CircRnas in atherosclerosis, with special emphasis on the spongy effect of circRnas on miRnas

C Cheng, Y Wang, Q Xue, Y Huang, X Wang, F Liao… - Cell Cycle, 2023 - Taylor & Francis
Atherosclerosis (AS) is a chronic inflammatory disease, which leads to atherosclerotic
rupture, lumen stenosis and thrombosis, and often endangers life. Circular RNAs (circRNAs) …