[HTML][HTML] The role of the ATP-binding cassette A1 (ABCA1) in human disease
L Jacobo-Albavera, M Domínguez-Pérez… - International journal of …, 2021 - mdpi.com
Cholesterol homeostasis is essential in normal physiology of all cells. One of several
proteins involved in cholesterol homeostasis is the ATP-binding cassette transporter A1 …
proteins involved in cholesterol homeostasis is the ATP-binding cassette transporter A1 …
[HTML][HTML] Cellular stress signaling and the unfolded protein response in retinal degeneration: mechanisms and therapeutic implications
T McLaughlin, A Medina, J Perkins, M Yera… - Molecular …, 2022 - Springer
Background The retina, as part of the central nervous system (CNS) with limited capacity for
self-reparation and regeneration in mammals, is under cumulative environmental stress due …
self-reparation and regeneration in mammals, is under cumulative environmental stress due …
The genetic basis for adult onset glaucoma: recent advances and future directions
Glaucoma, a diverse group of eye disorders that results in the degeneration of retinal
ganglion cells, is the world's leading cause of irreversible blindness. Apart from age and …
ganglion cells, is the world's leading cause of irreversible blindness. Apart from age and …
[HTML][HTML] miRNA studies in glaucoma: a comprehensive review of current knowledge and future perspectives
M Dobrzycka, A Sulewska, P Biecek… - International Journal of …, 2023 - mdpi.com
Glaucoma, a neurodegenerative disorder that leads to irreversible blindness, remains a
challenge because of its complex nature. MicroRNAs (miRNAs) are crucial regulators of …
challenge because of its complex nature. MicroRNAs (miRNAs) are crucial regulators of …
[HTML][HTML] Therapeutic drugs and devices for tackling ocular hypertension and glaucoma, and need for neuroprotection and cytoprotective therapies
NA Sharif - Frontiers in pharmacology, 2021 - frontiersin.org
Damage to the optic nerve and the death of associated retinal ganglion cells (RGCs) by
elevated intraocular pressure (IOP), also known as glaucoma, is responsible for visual …
elevated intraocular pressure (IOP), also known as glaucoma, is responsible for visual …
The essential role of docosahexaenoic acid and its derivatives for retinal integrity
D Swinkels, M Baes - Pharmacology & Therapeutics, 2023 - Elsevier
The fatty acid composition of photoreceptor outer segment (POS) phospholipids diverges
from other membranes, being highly enriched in polyunsaturated fatty acids (PUFAs). The …
from other membranes, being highly enriched in polyunsaturated fatty acids (PUFAs). The …
[HTML][HTML] Clinical pharmacology and pharmacogenetics of prostaglandin analogues in glaucoma
L Zhou, W Zhan, X Wei - Frontiers in Pharmacology, 2022 - frontiersin.org
Glaucoma is the main cause of irreversible visual loss worldwide, and comprises a group of
progressive, age-related, and chronic optic neuropathies. Prostaglandin analogs are …
progressive, age-related, and chronic optic neuropathies. Prostaglandin analogs are …
[HTML][HTML] Glaucoma heritability: Molecular mechanisms of disease
Glaucoma is one of the world's leading causes of irreversible blindness. A complex,
multifactorial disease, the underlying pathogenesis and reasons for disease progression are …
multifactorial disease, the underlying pathogenesis and reasons for disease progression are …
[HTML][HTML] MicroRNAs as biomarkers in glaucoma and potential therapeutic targets
B Martinez, PV Peplow - Neural regeneration research, 2022 - journals.lww.com
Glaucoma is a neurodegenerative disease in which optic nerve damage and visual field
defects occur. It is a leading cause of irreversible blindness. Its pathogenesis is largely …
defects occur. It is a leading cause of irreversible blindness. Its pathogenesis is largely …
Caveolar and non-Caveolar Caveolin-1 in ocular homeostasis and disease
EN Enyong, JM Gurley, ML De Ieso, WD Stamer… - Progress in retinal and …, 2022 - Elsevier
Caveolae, specialized plasma membrane invaginations present in most cell types, play
important roles in multiple cellular processes including cell signaling, lipid uptake and …
important roles in multiple cellular processes including cell signaling, lipid uptake and …