[HTML][HTML] Merkel cell polyomavirus: oncogenesis in a stable genome
MM Ahmed, CH Cushman, JA DeCaprio - Viruses, 2021 - mdpi.com
Merkel cell polyomavirus (MCV) is the causative agent for the majority of Merkel cell
carcinoma (MCC) cases. Polyomavirus-associated MCC (MCCP) is characterized by the …
carcinoma (MCC) cases. Polyomavirus-associated MCC (MCCP) is characterized by the …
Immunologic characteristics of nonmelanoma skin cancers: implications for immunotherapy.
ET Hall, E Fernandez-Lopez, AW Silk… - American Society of …, 2020 - europepmc.org
In this review, we summarize the immunology of nonmelanoma skin cancers (NMSCs) and
the clinical data with immunotherapy in this heterogeneous group of cancers that include …
the clinical data with immunotherapy in this heterogeneous group of cancers that include …
Immunotherapy for nonmelanoma skin cancer: facts and hopes
SZ Shalhout, HL Kaufman, KS Emerick… - Clinical Cancer Research, 2022 - AACR
Nonmelanoma skin cancer (NMSC) is the most frequently diagnosed malignancy in
humans, representing a broad range of cutaneous tumors. Keratinocyte carcinomas …
humans, representing a broad range of cutaneous tumors. Keratinocyte carcinomas …
[HTML][HTML] Single-cell dissection of Merkel cell carcinoma heterogeneity unveils transcriptomic plasticity and therapeutic vulnerabilities
Merkel cell carcinoma (MCC), a rare but aggressive skin cancer, remains a challenge in the
era of precision medicine. Immune checkpoint inhibitors (ICIs), the only approved therapy for …
era of precision medicine. Immune checkpoint inhibitors (ICIs), the only approved therapy for …
[HTML][HTML] Direct cellular reprogramming enables development of viral T antigen–driven Merkel cell carcinoma in mice
ME Verhaegen, PW Harms… - The Journal of …, 2022 - Am Soc Clin Investig
Merkel cell carcinoma (MCC) is an aggressive neuroendocrine skin cancer that frequently
carries an integrated Merkel cell polyomavirus (MCPyV) genome and expresses viral …
carries an integrated Merkel cell polyomavirus (MCPyV) genome and expresses viral …
[HTML][HTML] Immune checkpoint inhibition in non-melanoma skin Cancer: a review of current evidence
CJ Stonesifer, AR Djavid, JM Grimes, AE Khaleel… - Frontiers in …, 2021 - frontiersin.org
Immuno-oncology is a rapidly evolving field with growing relevance in the treatment of
numerous malignancies. The prior study of immunotherapy in dermatologic oncology has …
numerous malignancies. The prior study of immunotherapy in dermatologic oncology has …
[HTML][HTML] YAP1 and WWTR1 expression inversely correlates with neuroendocrine markers in Merkel cell carcinoma
Background Merkel cell carcinoma (MCC) is an aggressive neuroendocrine (NE) skin
cancer caused by severe UV-induced mutations or expression of Merkel cell polyomavirus …
cancer caused by severe UV-induced mutations or expression of Merkel cell polyomavirus …
[HTML][HTML] An updated review of the biomarkers of response to immune checkpoint inhibitors in Merkel cell carcinoma: Merkel cell carcinoma and immunotherapy
Simple Summary Merkel cell carcinoma (MCC) is a rare and highly aggressive type of skin
neuroendocrine cancer that frequently recurs and metastasizes within a relatively short …
neuroendocrine cancer that frequently recurs and metastasizes within a relatively short …
Beyond tumor PD-L1: emerging genomic biomarkers for checkpoint inhibitor immunotherapy
Despite the success of immune checkpoint blockade as a strategy for activating an antitumor
immune response and promoting cancer regression, only a subset of patients have durable …
immune response and promoting cancer regression, only a subset of patients have durable …
[HTML][HTML] Merkel cell carcinoma: an immunotherapy fairy-tale?
ET Tanda, AL d'Amato, G Rossi, E Croce… - Frontiers in …, 2021 - frontiersin.org
Merkel cell carcinoma (MCC) is a rare, highly aggressive, neuroendocrine cutaneous tumor.
The incidence of MCC is growing worldwide, and the disease-related mortality is about three …
The incidence of MCC is growing worldwide, and the disease-related mortality is about three …