Merkel cell carcinoma: an immunotherapy fairy-tale?
ET Tanda, AL d'Amato, G Rossi, E Croce… - Frontiers in …, 2021 - frontiersin.org
Merkel cell carcinoma (MCC) is a rare, highly aggressive, neuroendocrine cutaneous tumor.
The incidence of MCC is growing worldwide, and the disease-related mortality is about three …
The incidence of MCC is growing worldwide, and the disease-related mortality is about three …
Predominance of central memory T cells with high T-cell receptor repertoire diversity is associated with response to PD-1/PD-L1 inhibition in Merkel cell carcinoma
I Spassova, S Ugurel, P Terheyden, A Sucker… - Clinical Cancer …, 2020 - AACR
Purpose: Merkel cell carcinoma (MCC) is an aggressive neuroendocrine skin cancer, which
can be effectively controlled by immunotherapy with PD-1/PD-L1 checkpoint inhibitors …
can be effectively controlled by immunotherapy with PD-1/PD-L1 checkpoint inhibitors …
[HTML][HTML] RB1-deficient squamous cell carcinoma: The proposed source of combined Merkel cell carcinoma
RC DeCoste, NM Walsh, D Gaston, TY Ly, S Pasternak… - Modern Pathology, 2022 - Elsevier
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine (NE) carcinoma
arising from integration of Merkel cell polyomavirus (MCPyV) DNA into a host cell or from …
arising from integration of Merkel cell polyomavirus (MCPyV) DNA into a host cell or from …
[HTML][HTML] Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of nonmelanoma skin cancer
Nonmelanoma skin cancers (NMSCs) are some of the most commonly diagnosed
malignancies. In general, early-stage NMSCs have favorable outcomes; however, a small …
malignancies. In general, early-stage NMSCs have favorable outcomes; however, a small …
Merkel cell carcinoma
Merkel cell carcinoma (MCC) is a rare and extremely aggressive neuroendocrine carcinoma
of the skin, with increasing incidence worldwide. This review intends to propose a …
of the skin, with increasing incidence worldwide. This review intends to propose a …
[HTML][HTML] International increases in Merkel cell carcinoma incidence rates between 1997 and 2016
Relatively little is known about the epidemiology of Merkel cell carcinoma (MCC) with regard
to international trends in incidence, specifically relating to differences by age, sex, and …
to international trends in incidence, specifically relating to differences by age, sex, and …
Shaping the future of immunotherapy targets and biomarkers in melanoma and non-melanoma cutaneous cancers
P Spiliopoulou, O Vornicova, S Genta… - International Journal of …, 2023 - mdpi.com
Recent advances in treating cutaneous melanoma have resulted in impressive patient
survival gains. Refinement of disease staging and accurate patient risk classification have …
survival gains. Refinement of disease staging and accurate patient risk classification have …
Distinct regulation of EZH2 and its repressive H3K27me3 mark in polyomavirus-positive and-negative Merkel cell carcinoma
MA Durand, A Drouin, A Mouchard, L Durand… - Journal of Investigative …, 2023 - Elsevier
Merkel cell carcinoma (MCC) is an aggressive skin cancer for which Merkel cell
polyomavirus integration and expression of viral oncogenes small T and Large T have been …
polyomavirus integration and expression of viral oncogenes small T and Large T have been …
DNA-methylation patterns imply a common cellular origin of virus-and UV-associated Merkel cell carcinoma
J Gravemeyer, I Spassova, ME Verhaegen, AA Dlugosz… - Oncogene, 2022 - nature.com
Merkel cell carcinoma (MCC) is a neuroendocrine tumor either induced by integration of the
Merkel cell polyomavirus into the cell genome or by accumulation of UV-light-associated …
Merkel cell polyomavirus into the cell genome or by accumulation of UV-light-associated …
Merkel cell carcinoma: an update
RC DeCoste, MD Carter, TY Ly, JR Gruchy… - Human Pathology, 2023 - Elsevier
Merkel cell carcinoma (MCC) is an uncommon primary cutaneous neuroendocrine
carcinoma associated with an adverse prognosis. In recent years, our understanding of …
carcinoma associated with an adverse prognosis. In recent years, our understanding of …