Genetic basis of metabolome variation in yeast

JS Breunig, SR Hackett, JD Rabinowitz… - PLoS …, 2014 - journals.plos.org
Metabolism, the conversion of nutrients into usable energy and biochemical building blocks,
is an essential feature of all cells. The genetic factors responsible for inter-individual …

The cardiac sodium channel is post-translationally modified by arginine methylation

P Beltran-Alvarez, S Pagans… - Journal of proteome …, 2011 - ACS Publications
The α subunit of the cardiac sodium channel (Nav1. 5) is an essential protein in the initial
depolarization phase of the cardiomyocyte action potential. Post-translational modifications …

Hypotensive effect of S-adenosyl-l-methionine in hypertensive rats is reduced by autonomic ganglia and KATP channel blockers

M Sikora, K Pham, M Ufnal - Amino Acids, 2016 - Springer
Abstract S-adenosyl-l-methionine (SAM) is an amino acid involved in a number of
physiological processes in the nervous system. Some evidence suggests a therapeutic …

Electrical polarity-dependent gating and a unique subconductance of RyR2 induced by S-adenosyl methionine via the ATP binding site

AJ Kampfer, EM Balog - The Journal of Biochemistry, 2021 - academic.oup.com
Abstract S-Adenosyl-L-methionine (SAM) was used to probe the functional effects exerted
via the cardiac RyR isoform (RyR2) adenine nucleotide binding site. Single channel …

Regulation of the cardiac isoform of the ryanodine receptor by S-adenosyl-l-methionine

AK Gaboardi - 2011 - repository.gatech.edu
Abstract Activity of the Ryanodine Receptor (RyR2)(aka cardiac Ca2+ release channel)
plays a pivotal role in contraction of the heart. S-adenosyl-l-methionine (SAM) is a biological …