Growing evidence suggests a possible involvement of the intestinal microbiota in generating
new neurons, but a detailed breakdown of the microbiota composition is lacking. In this …

Major depressive disorder (MDD) is a complex disorder and a leading cause of disability in
280 million people worldwide. Many environmental factors, such as microbes, drugs, and …

Depression remains one of the most prevalent psychiatric disorders, and it has been
confirmed that it is related to the dysfunction of the microbiota–gut–brain axis. Manipulation …

Modern neurological approaches enable detailed studies on the pathophysiology and
treatment of depression. An imbalance in the microbiota–gut–brain axis contributes to the …

Introduction Psychological stress can induce affective disorders. Gut microbiota plays a vital
role in emotional function regulation; however, the association between gut microbiota and …

Methods Sixty C57BL/6 mice (both male and female) were divided into two groups by
gender. Same gender mice were then divided randomly into the non-treated control group …

In recent years there has been a rapid rise in interest for the application of probiotic
supplements to act as mediators in health and disease. This appeal is predominantly due to …

The brain-derived neurotrophic factor (BDNF) is an extensively studied neurotrophin es
sential for both developing the brain and maintaining adult brain function. In the adult …

Background Puerarin is an isoflavone derivative isolated from the traditional Chinese
medicine Pueraria Lobelia, which has proven to relieve depression-like behavior. However …

Depression is a progressive neurodegenerative disease characterized by cognitive deficits
and psychiatric symptoms. The gut microbiota-brain axis plays a pivotal role during …