Accidents evoked by venomous animals are common in tropical regions. In Brazil,
envenomation evoked by snakes, spiders and scorpions are an important public health …

Background Nitric oxide (NO) is a multifunctional signaling molecule that regulates important
cellular events in inflammation including leukocyte recruitment. Previous studies have …

Crotoxin is the main neurotoxic component of Crotalus durissus terrificus snake venom and
modulates immune and inflammatory responses, interfering with the activity of leukocytes. In …

Achyrocline satureioides (Lam.) DC is a herb native to South America, and its inflorescences
are popularly employed to treat inflammatory diseases. Here, the effects of the in vivo …

Uncaria guianensis (Aublet) JF Gmelin is an herbal medicine from tropical areas of South
and Central America. We investigated the anti-inflammatory and anti-allergic properties of …

In recent years, extensive research has delved into the pathophysiology of local reactions
triggered by Bothrops snake venoms. Even though antivenom works well at reducing death …

AIM: To observe the anti-cancer effect of iNOS selective inhibitor (aminoguanidine, AG) and
investigate the relationship between iNOS inhibitor and angiogenesis, infiltration or …

Background: N-octadecanoyl-5-hydroxytryptamide (C18-5HT) is an amide that can be
obtained by the coupling of serotonin and octadecanoic acid. This study aims to characterize …

The compound (5Z)-5-[(5-bromo-1H-indol-3-yl) methylene]-3-(4-chlorobenzyl)-thiazolidine-
2, 4-dione (LYSO-7) was synthesised in order to obtain a new type of anti-inflammatory drug …

Phenol (PHE) and hydroquinone (HQ) are metabolites of benzene that affect leukocytes
after solvent intoxication. Hence, we investigated the effects of PHE or HQ exposure on …