A cross-talk about radioresistance in lung cancer—How to improve radiosensitivity according to Chinese medicine and medicaments that commonly occur in …

P Nowak, I Bil-Lula, M Śliwińska-Mossoń - International Journal of …, 2023 - mdpi.com
Lung cancer is one of the most common cancers in the population and is characterized by
non-specific symptoms that delay the diagnosis and reduce the effectiveness of oncological …

Molecular mechanism of tanshinone against prostate cancer

W Li, T Huang, S Xu, B Che, Y Yu, W Zhang, K Tang - Molecules, 2022 - mdpi.com
Prostate cancer (PCa) is the most common malignant tumor of the male urinary system in
Europe and America. According to the data in the World Cancer Report 2020, the incidence …

Salvianolic acid B from Salvia miltiorrhiza bunge: A potential antitumor agent

SS Guo, ZG Wang - Frontiers in Pharmacology, 2022 - frontiersin.org
Salvia miltiorrhiza Bunge (Lamiaceae) is a perennial herb widely found in China since
ancient times with a high economic and medicinal value. Salvianolic acid B (Sal-B) is an …

PLA2G2A Phospholipase Promotes Fatty Acid Synthesis and Energy Metabolism in Pancreatic Cancer Cells with K-ras Mutation

M Zhang, R Xiang, C Glorieux, P Huang - International Journal of …, 2022 - mdpi.com
Oncogenic K-ras is often activated in pancreatic ductal adenocarcinoma (PDAC) due to
frequent mutation (> 90%), which drives multiple cellular processes, including alterations in …

Dihydrotanshinone I protects human chondrocytes and alleviates damage from spontaneous osteoarthritis in a guinea pig model

YZ Zhang, ZJ Wei, SN Yu, XY Wang, Y Wang… - Scientific Reports, 2023 - nature.com
Osteoarthritis (OA) is the most common degenerative joint disease. Currently, no satisfactory
pharmacological treatment exists for OA. The potential anti-inflammatory properties of …

Quercetin and tanshinone prevent mitochondria from oxidation and autophagy to inhibit KGN cell apoptosis through the SIRT1/SIRT3-FOXO3a axis

Q Wan, L Tang, K Jin, X Chen, Y Li… - Cellular and Molecular …, 2024 - cellmolbiol.org
Granulosa cells are somatic cells located inside follicles that play a crucial role in the growth
and development of follicles. Quercetin and tanshinone are two key monomers in traditional …

Dihydrotanshinone I inhibits hepatocellular carcinoma cells proliferation through DNA damage and EGFR pathway

L Wang, X Xu, D Chen, C Li - PeerJ, 2023 - peerj.com
Background The incidence and mortality of hepatocellular carcinoma (HCC) are globally on
the rise. Dihydrotanshinone I, a natural product isolated from Salvia miltiorrhiza Bunge, has …

Diterpenoid quinones from the Salvia miltiorrhiza and their lung protective activity

YJ Ren, YG Cao, MN Zeng, QQ Zhang, YL Liu, C He… - Fitoterapia, 2023 - Elsevier
Abstract Seven new diterpenoids quinones (1–6), together with five known ones (7–11),
were isolated from the roots of Salvia miltiorrhiza Bunge. Their structures were elucidated by …

[HTML][HTML] Nanodelivery System of Traditional Chinese Medicine Bioactive Compounds: Application in the Treatment of Prostate Cancer

B Zou, Y Long, R Gao, Q Liu, X Tian, B Liu, Q Zhou - Phytomedicine, 2024 - Elsevier
Background The long history of clinical experience in China have confirmed the
effectiveness of traditional Chinese medicine (TCM) in treating prostate cancer (PCa). Until …

Improvement of Neuronal and Cognitive Functions Following Treatment with 3', 4'Dihydroxyflavonol in Experimental Focal Cerebral Ischemia-Reperfusion Injury in …

T Aladag, G Acar, R Mogulkoc, AK Baltaci - European Journal of …, 2024 - Elsevier
Introduction Ischemia/reperfusion is a pathological condition by the restoration of perfusion
and oxygenation following a period of restricted blood flow to an organ. To address existing …