A polyp is defined as any mass protruding into the lumen of a hollow viscus. Colorectal
polyps may be classified by their macroscopic appearance as sessile (flat, arising directly …

The trillions of bacteria that naturally reside in the human gut collectively constitute the
complex system known the gut microbiome, a vital player for the host's homeostasis and …

A subset of colorectal cancer shows significant accumulation of aberrant promoter
methylation. Previously, we developed two groups of methylation markers that classified …

Colorectal cancer and adenoma adjacent to cancer exhibit distinct microRNA (miRNA)
alterations in an apparent mucosa-to-adenocarcinoma sequence. The pattern of microRNAs …

Lifetime risk of developing colorectal cancer is 5%, and 5-year survival at early stage is 92%.
Individuals with precancerous lesions removed at primary screening are typically …

Colorectal polyps have been traditionally classified as either hyperplastic or adenomatous,
with only the latter progressing to carcinoma. However, it is now recognized that certain …

Colorectal cancers develop via two major pathways that include chromosomal instability and
microsatellite instability. Microsatellite instability occurs due to deficient DNA mismatch …

Aim The study investigated whether autophagic activity and hypoxia parallel the adenoma–
carcinoma sequence. Method The study comprised 120 tubular adenomas with high‐grade …

One of the major frontiers of translational gastroenterological research remains the
development of adjunct approaches to improve the performance of colonoscopy. There have …

Background In the past decade, there have been significant changes in the classification
and nomenclature of colorectal polyps. Previously, only two groups of lesions were widely …