Protection against stroke with glucagon-like peptide-1 receptor agonists: a comprehensive review of potential mechanisms

B Vergès, V Aboyans, D Angoulvant… - Cardiovascular …, 2022 - Springer
Several randomized controlled trials have demonstrated the benefits of glucagon-like
peptide-1 receptor agonists (GLP-1RAs) on ischemic stroke in patients with diabetes. In this …

An update on the molecular and cellular basis of pharmacotherapy in type 2 diabetes mellitus

MO Mahgoub, II Ali, JO Adeghate, K Tekes… - International journal of …, 2023 - mdpi.com
Diabetes mellitus (DM) is a chronic illness with an increasing global prevalence. More than
537 million cases of diabetes were reported worldwide in 2021, and the number is steadily …

Benefits and risks of drug combination therapy for diabetes mellitus and its complications: a comprehensive review

X Xie, C Wu, Y Hao, T Wang, Y Yang, P Cai… - Frontiers in …, 2023 - frontiersin.org
Diabetes is a chronic metabolic disease, and its therapeutic goals focus on the effective
management of blood glucose and various complications. Drug combination therapy has …

[HTML][HTML] Therapeutic application of natural compounds for skeletal muscle-associated metabolic disorders: A review on diabetes perspective

K Ahmad, S Shaikh, JH Lim, SS Ahmad… - Biomedicine & …, 2023 - Elsevier
Skeletal muscle (SM) plays a vital role in energy and glucose metabolism by regulating
insulin sensitivity, glucose uptake, and blood glucose homeostasis. Impaired SM …

Pharmacological support for the treatment of obesity—present and future

M Kosmalski, K Deska, B Bąk, M Różycka-Kosmalska… - Healthcare, 2023 - mdpi.com
Obesity is a growing civilization problem, associated with a number of negative health
consequences affecting almost all tissues and organs. Currently, obesity treatment includes …

How far beyond diabetes can the benefits of glucagon-like peptide-1 receptor agonists go? A review of the evidence on their effects on hepatocellular carcinoma

K Arvanitakis, T Koufakis, K Kotsa, G Germanidis - Cancers, 2022 - mdpi.com
Simple Summary Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) were drugs
originally intended for the management of diabetes, while their role on the treatment of …

Anti-inflammatory role of glucagon-like peptide 1 receptor agonists and its clinical implications

SH Alharbi - Therapeutic Advances in Endocrinology and …, 2024 - journals.sagepub.com
Glucagon-like peptide 1 receptor agonists (GLP-1RAs) have emerged as promising
therapeutic agents with potent anti-inflammatory properties and diverse clinical implications …

Efficacy and safety of glucagon-like peptide-1 receptor agonists on body weight and cardiometabolic parameters in individuals with obesity and without diabetes: a …

HUH Ansari, SU Qazi, F Sajid, Z Altaf, S Ghazanfar… - Endocrine Practice, 2024 - Elsevier
Objective Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), initially for type 2
diabetes mellitus, show promise in promoting weight loss and improving heart health in …

Phenotyping obesity: a focus on metabolically healthy obesity and metabolically unhealthy normal weight

R Agius, NP Pace, S Fava - Diabetes/Metabolism Research and …, 2024 - Wiley Online Library
Over the past 4 decades, research has shown that having a normal body weight does not
automatically imply preserved metabolic health and a considerable number of lean …

Medical weight optimization for arthroplasty patients: a primer of emerging therapies for the joint arthroplasty surgeon

CK Mayfield, MA Mont, JR Lieberman… - The Journal of …, 2024 - Elsevier
The obesity epidemic in the United States continues to grow with more than 40% of
individuals now classified as obese (body mass index> 30). Obesity has been readily …