[HTML][HTML] The role of inspiratory flow in selection and use of inhaled therapy for patients with chronic obstructive pulmonary disease
DA Mahler - Respiratory Medicine, 2020 - Elsevier
Inhalation therapy is the mainstay of chronic obstructive pulmonary disease management,
and inhaler selection can have a profound impact on drug delivery and medication …
and inhaler selection can have a profound impact on drug delivery and medication …
Lung deposition and inspiratory flow rate in patients with chronic obstructive pulmonary disease using different inhalation devices: a systematic literature review and …
A Baloira, A Abad, A Fuster… - … Journal of Chronic …, 2021 - Taylor & Francis
Background Our aim was to describe: 1) lung deposition and inspiratory flow rate; 2) main
characteristics of inhaler devices in chronic obstructive pulmonary disease (COPD) …
characteristics of inhaler devices in chronic obstructive pulmonary disease (COPD) …
Comparison of peak inspiratory flow rate via the Breezhaler®, Ellipta® and HandiHaler® dry powder inhalers in patients with moderate to very severe COPD: a …
P Altman, L Wehbe, J Dederichs, T Guerin… - BMC pulmonary …, 2018 - Springer
Background The chronic and progressive nature of chronic obstructive pulmonary disease
(COPD) requires self-administration of inhaled medication. Dry powder inhalers (DPIs) are …
(COPD) requires self-administration of inhaled medication. Dry powder inhalers (DPIs) are …
A review of upper airway physiology relevant to the delivery and deposition of inhalation aerosols
Developing effective oral inhaled drug delivery treatment strategies for respiratory diseases
necessitates a thorough knowledge of the respiratory system physiology, such as the …
necessitates a thorough knowledge of the respiratory system physiology, such as the …
Numerical study on the effect of the realistic mouth-inhaler positions on orally inhaled drug delivery in pediatric intersubject upper airways
The relative position between the pediatric upper airway and the inhalation device during
real inhalation administration has significant effects on the delivery efficiency of orally …
real inhalation administration has significant effects on the delivery efficiency of orally …
Measuring peak inspiratory flow in patients with chronic obstructive pulmonary disease
JA Ohar, GT Ferguson, DA Mahler… - … journal of chronic …, 2022 - Taylor & Francis
Dry powder inhalers (DPIs) are breath actuated, and patients using DPIs need to generate
an optimal inspiratory flow during the inhalation maneuver for effective drug delivery to the …
an optimal inspiratory flow during the inhalation maneuver for effective drug delivery to the …
Inhaler technique in asthma and COPD: challenges and unmet knowledge that can contribute to suboptimal use in real life
AS Melani - Expert Review of Clinical Pharmacology, 2021 - Taylor & Francis
Introduction: Inhalers are the most commonly used devices for lung drug delivery in asthma
and COPD. Inhaler use offers several advantages but requires the user's proper mastery …
and COPD. Inhaler use offers several advantages but requires the user's proper mastery …
State-of-the-art review of the application and development of various methods of aerosol therapy
M Matuszak, M Ochowiak, S Włodarczak… - International Journal of …, 2022 - Elsevier
Aerosol therapy is a rapidly developing field of science. Due to a number of advantages, the
administration of drugs to the body with the use of aerosol therapy is becoming more and …
administration of drugs to the body with the use of aerosol therapy is becoming more and …
Combining experimental and computational techniques to understand and improve dry powder inhalers
ABSTRACT Introduction Dry Powder Inhalers (DPIs) continue to be developed to deliver an
expanding range of drugs to treat an ever-increasing range of medical conditions; with each …
expanding range of drugs to treat an ever-increasing range of medical conditions; with each …
Potential effects of inhaler mouthpiece size on particle deposition in the human upper airway
Understanding the impact of inhaler mouthpiece sizes on particle transport and deposition in
the human upper airway is important to optimize inhaler designs toward improving the …
the human upper airway is important to optimize inhaler designs toward improving the …