One of the mechanisms of the antitumor activity of green tea (−)‐epigallocatechin‐3‐gallate
(EGCG) is associated with its effect on epidermal growth factor receptor (EGFR)‐mediated …

Osimertinib (OSI), also known as AZD9291, is a third-generation epidermal growth factor
receptor (EGFR) tyrosine kinase inhibitor that has been approved for the treatment of non …

Hepatocellular carcinoma (HCC) is one of the most common cancer-related causes of death
worldwide. Due to very poor 5-year-survival new therapeutic approaches are mandatory …

Herein, we report the synthesis of a series of new fourteen iodoquinazoline derivatives 7a-c
to 13a-e and their evaluation as potential anticancer agents via dual targeting of EGFR …

Hepatocellular carcinoma is highly refractory cancer which is resistant to conventional
chemotherapy and radiotherapy, carrying a dismal prognosis. Although many anticancer …

Protein kinase CK2, formerly referred to as casein kinase II, is a serine/threonine kinase
often found overexpressed in solid tumors and hematologic malignancies that …

Redox regulation of epidermal growth factor receptor (EGFR) signaling helps protect cells
against oxidative stress. In this study, we investigated whether the cytotoxicity of an EGFR …

A majority of patients with HCC present with advanced disease and are not candidates for
liver transplantation, surgical resection, or regional therapy. Systemic cytotoxic …

Introduction: Thiazole is a well-known five-membered heterocyclic compound. Various
methods have been worked out for its synthesis. In the last few decades, a lot of work has …

Structured nanoassemblies are biomimetic structures that are enabling applications from
nanomedicine to catalysis. One approach to achieve these spatially organized architectures …