[HTML][HTML] Dual induction of caspase 3-and transglutaminase-dependent apoptosis by acyclic retinoid in hepatocellular carcinoma cells
H Tatsukawa, T Sano, Y Fukaya, N Ishibashi… - Molecular cancer, 2011 - Springer
Background Hepatocellular carcinoma has a high mortality rate due to its rate of recurrence.
Acyclic retinoid prevents recurrence of hepatocellular carcinoma in patients after surgical …
Acyclic retinoid prevents recurrence of hepatocellular carcinoma in patients after surgical …
Targeting tyrosine kinase receptors in hepatocellular carcinoma
J Muntane, AJ De la Rosa, F Docobo… - Current cancer drug …, 2013 - ingentaconnect.com
The recent discoveries of genomic and molecular markers in hepatocellular carcinoma
(HCC) have improved the understanding about the complexity of the signal transduction …
(HCC) have improved the understanding about the complexity of the signal transduction …
Dissection of signal transduction pathways as a tool for the development of targeted therapies of hepatocellular carcinoma
DF Calvisi, RM Pascale, F Feo - Reviews on recent clinical …, 2007 - ingentaconnect.com
Genomic instability during hepatocarcinogenesis causes changes in signal transduction
network. Strategies for identification of new markers/therapeutic targets include discovery of …
network. Strategies for identification of new markers/therapeutic targets include discovery of …
[HTML][HTML] Adverse toxic effects of tyrosine kinase inhibitors on non-target zebrafish liver (ZFL) cells
Over the past 20 years, numerous tyrosine kinase inhibitors (TKIs) have been introduced for
targeted therapy of various types of malignancies. Due to frequent and increasing use …
targeted therapy of various types of malignancies. Due to frequent and increasing use …
Erlotinib-loaded albumin nanoparticles: A novel injectable form of erlotinib and its in vivo efficacy against pancreatic adenocarcinoma ASPC-1 and PANC-1 cell lines
Erlotinib was loaded on albumin nanoparticles for the first time and the cytotoxic effect of the
resulting nanoparticles against ASPC-1 and PANC-1 pancreatic adenocarcinoma cell lines …
resulting nanoparticles against ASPC-1 and PANC-1 pancreatic adenocarcinoma cell lines …
Oridonin inhibits cell growth by induction of apoptosis on human hepatocelluar carcinoma BEL-7402 cells
JF Zhang, JJ Liu, PQ Liu, DJ Lin, XD Li, GH Chen - Hepatology research, 2006 - Elsevier
The present study was undertaken to investigate the mechanisms of oridonin induced
apoptosis on human hepatocellular carcinoma BEL-7402 cells. BEL-7402 cells in culture …
apoptosis on human hepatocellular carcinoma BEL-7402 cells. BEL-7402 cells in culture …
[HTML][HTML] Targeting TF-AKT/ERK-EGFR pathway suppresses the growth of hepatocellular carcinoma
SZ Huang, MN Wei, JR Huang, ZJ Zhang… - Frontiers in …, 2019 - frontiersin.org
Tissue factor (TF) is a transmembrane glycoprotein to initiate blood coagulation and
frequently overexpressed in a variety of tumors. Our previous study has showed that the …
frequently overexpressed in a variety of tumors. Our previous study has showed that the …
[HTML][HTML] Signaling pathways involved in the inhibition of epidermal growth factor receptor by erlotinib in hepatocellular cancer
A Huether, M Höpfner, AP Sutter… - World journal of …, 2006 - ncbi.nlm.nih.gov
AIM: To examine the underlying mechanisms of erlotinib-induced growth inhibition in
hepatocellular carcinoma (HCC). METHODS: Erlotinib-induced alterations in gene …
hepatocellular carcinoma (HCC). METHODS: Erlotinib-induced alterations in gene …
Current discovery strategies for hepatocellular carcinoma therapeutics
Q Dai, C Zhang, Z Yuan, Q Sun… - Expert opinion on drug …, 2020 - Taylor & Francis
Introduction: The global incidence of hepatocellular carcinoma (HCC) is not expected to
decline significantly over the next 30 years. And although the latest gene sequencing …
decline significantly over the next 30 years. And although the latest gene sequencing …
Molecular genetics and targeted therapy in hepatocellular carcinoma
EI Marks, NS Yee - Current cancer drug targets, 2016 - ingentaconnect.com
Hepatocellular carcinoma (HCC) is a highly lethal disease, therefore effective and tolerable
treatment is urgently needed. In this article, we provide an updated review of the genetic …
treatment is urgently needed. In this article, we provide an updated review of the genetic …