Thrombectomy vs medical management in low NIHSS acute anterior circulation stroke

O Volny, C Zerna, A Tomek, M Bar, M Rocek, R Padr… - Neurology, 2020 - AAN Enterprises
Objective To undertake an effectiveness and safety analysis of EVT in patients with LVO and
NIH Stroke Scale (NIHSS) score≤ 6 using datasets of multicenter and multinational nature …

Outcome of patients with occlusions of the internal carotid artery or the main stem of the middle cerebral artery with NIHSS score of less than 5: comparison between …

MR Heldner, S Jung, C Zubler, P Mordasini… - Journal of Neurology …, 2015 - jnnp.bmj.com
Background and purpose The use of thrombolysis in patients with minor neurological deficits
and large vessel occlusion is controversial. Methods We compared the outcome of patients …

The Chinese Stroke Association scientific statement: intravenous thrombolysis in acute ischaemic stroke

Q Dong, Y Dong, L Liu, A Xu, Y Zhang… - Stroke and Vascular …, 2017 - svn.bmj.com
The most effective medical treatment for acute ischaemic stroke (AIS) is to offer intravenous
thrombolysis during the ultra-early period of time after the onset. Even based on the …

Outcome of endovascular therapy in stroke with large vessel occlusion and mild symptoms

C Manno, G Disanto, G Bianco, S Nannoni, M Heldner… - Neurology, 2019 - AAN Enterprises
Objective To compare outcomes after endovascular therapy (EVT) and IV thrombolysis (IVT)
in patients with stroke with emergent large vessel occlusion (LVO) and mild neurologic …

Endovascular mechanical thrombectomy in large-vessel occlusion ischemic stroke presenting with low national institutes of health stroke scale: systematic review and …

CJ Griessenauer, C Medin, J Maingard, RV Chandra… - World neurosurgery, 2018 - Elsevier
Introduction Mechanical thrombectomy has become the standard of care for management of
most large vessel occlusion (LVO) strokes. When patients with LVO present with minor …

Ischemic stroke: advances in diagnosis and management

CR Cassella, A Jagoda - Emergency Medicine Clinics, 2017 - emed.theclinics.com
Ischemic Stroke - Emergency Medicine Clinics Skip to Main Content Emergency Medicine Clinics
Log in Register Log in Subscribe Claim Cart (8 items)8 Skip menu theclinics.com theclinics.com …

The exact science of stroke thrombolysis and the quiet art of patient selection

JS Balami, G Hadley, BA Sutherland, H Karbalai… - Brain, 2013 - academic.oup.com
The science of metric-based patient stratification for intravenous thrombolysis, revolutionized
by the landmark National Institute of Neurological Disorders and Stroke trial, has …

Review, historical context, and clarifications of the NINDS rt-PA stroke trials exclusion criteria: part 1: rapidly improving stroke symptoms

SR Levine, P Khatri, JP Broderick, JC Grotta… - Stroke, 2013 - Am Heart Assoc
Background and Purpose—Since Food and Drug Administration approval of intravenous
tissue-type plasminogen activator (tPA) for treatment of acute ischemic stroke in 1996, it has …

Strokes with minor symptoms: an exploratory analysis of the National Institute of Neurological Disorders and Stroke recombinant tissue plasminogen activator trials

P Khatri, DO Kleindorfer, SD Yeatts, JL Saver… - Stroke, 2010 - Am Heart Assoc
Background and Purpose—The pivotal National Institute of Neurological Disorders and
Stroke recombinant tissue plasminogen activator trials excluded patients with ischemic …

Molecular disorganization of axons adjacent to human lacunar infarcts

JD Hinman, MD Lee, S Tung, HV Vinters… - Brain, 2015 - academic.oup.com
Cerebral microvascular disease predominantly affects brain white matter and deep grey
matter, resulting in ischaemic damage that ranges from lacunar infarcts to white matter …