Cellular senescence is a ubiquitous process with roles in tissue remodelling, including
wound repair and embryogenesis. However, prolonged senescence can be maladaptive …

Cellular senescence, classically defined as stable cell cycle arrest, is implicated in biological
processes such as embryogenesis, wound healing and ageing. Senescent cells have a …

Bone marrow derived stem cells (BMSCs) transplantation are viewed as a promising
therapeutic candidate for spinal cord injury (SCI). However, the inflammatory …

Bone marrow mesenchymal stem cell (BMSC) is previously reported to present a certain
effect on treating spinal cord injury (SCI), while the underlying mechanism is largely …

Stem cell therapy can be used to repair and regenerate damaged hearts tissue;
nevertheless, the low survival rate of transplanted cells limits their therapeutic efficacy …

The transplantation of bone marrow-derived mesenchymal stem cells (BMMSCs) alleviates
neuropathology and improves cognitive deficits in animal models with Alzheimer's disease …

Objectives The aim of this study was to investigate the effects of exosomes isolated from
human bone marrow mesenchymal stem cells (BMSCs) on osteoarthritis (OA) and a …

Purpose: Extracellular Vesicles (EVs) derived from hMSCs, have the potential to alleviate
cartilage damage and inflammation. We aimed to explore the effects of EVs derived from …

Objective Cardiomyocyte senescence is an important contributor to cardiovascular diseases
and can be induced by stressors including DNA damage, oxidative stress, mitochondrial …

Background: Premature senescence occurs in adult hepatobiliary diseases and worsens the
prognosis through deleterious liver remodeling and hepatic dysfunction. Senescence might …