The genus Cryptococcus contains two primary species complexes that are significant
opportunistic human fungal pathogens: C. neoformans and C. gattii. In humans …

The human pathogenic fungus Cryptococcus neoformans is a global health concern.
Previous research in the field has focused on studies using reference strains to identify …

Environmental pathogens move from ecological niches to mammalian hosts, requiring
adaptation to dramatically different environments. Microbes that disseminate farther …

Candida albicans is a pathobiont that colonizes multiple niches in the body including the
gastrointestinal (GI) tract but is also responsible for both mucosal and systemic infections …

The pathogenic yeast Cryptococcus neoformans produces polyploid titan cells in response
to the host lung environment that are critical for host adaptation and subsequent disease …

The fungal genus Cryptococcus comprises a group of pathogens with considerable
phenotypic and genotypic diversity that can lead to cryptococcosis in both healthy and …

Cryptococcus is the leading cause of AIDS-related meningitis in sub-Saharan Africa. The
clinical implications of a sterile cerebrospinal fluid (CSF) culture among individuals …

The pathogenic yeast Cryptococcus neoformans causes nearly 200,000 deaths annually in
immunocompromised individuals. Cryptococcus cells can undergo substantial …

Monothiol glutaredoxins are important regulators of iron homeostasis that play conserved
roles in the sensing and trafficking of iron-sulfur clusters. We previously characterized the …

Isolates of Cryptococcus neoformans, a fungal pathogen that kills over 112,000 people each
year, differ from a 19-Mb reference genome at a few thousand up to almost a million DNA …