Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical Reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Organic photosensitizers for antimicrobial phototherapy

VN Nguyen, Z Zhao, BZ Tang, J Yoon - Chemical Society Reviews, 2022 - pubs.rsc.org
Microbial infectious diseases, especially those caused by new and antibiotic-resistant
pathogenic microbes, have become a significant threat to global human health. As an …

Aggregation-induced emission (AIE), life and health

H Wang, Q Li, P Alam, H Bai, V Bhalla, MR Bryce… - ACS …, 2023 - ACS Publications
Light has profoundly impacted modern medicine and healthcare, with numerous
luminescent agents and imaging techniques currently being used to assess health and treat …

Recent advances of AIE light-up probes for photodynamic therapy

S Liu, G Feng, BZ Tang, B Liu - Chemical science, 2021 - pubs.rsc.org
As a new non-invasive treatment method, photodynamic therapy (PDT) has attracted great
attention in biomedical applications. The advantages of possessing fluorescence for …

Aggregation‐enhanced theranostics: AIE sparkles in biomedical field

M Kang, Z Zhang, N Song, M Li, P Sun, X Chen… - …, 2020 - Wiley Online Library
Theranostics referring to the ingenious integration of diagnostics and therapeutics has
garnered tremendous attention in these years as it provides a promising opportunity for …

Aggregation‐induced emission: recent advances in materials and biomedical applications

X Cai, B Liu - Angewandte Chemie International Edition, 2020 - Wiley Online Library
The concept of aggregation‐induced emission (AIE) has opened new opportunities in many
research fields. Motivated by the unique feature of AIE fluorogens (AIEgens), during the past …

Gathering brings strength: How organic aggregates boost disease phototheranostics

J Qi, H Ou, Q Liu, D Ding - Aggregate, 2021 - Wiley Online Library
Phototheranostics that concurrently and complementarily integrate real‐time diagnosis and
in situ therapeutic capabilities in one platform has become the advancing edge of precision …

[PDF][PDF] The concept and examples of type-III photosensitizers for cancer photodynamic therapy

Q Yao, J Fan, S Long, X Zhao, H Li, J Du, K Shao… - Chem, 2022 - cell.com
In conventional photodynamic therapy (PDT), reactive oxygen species are produced to kill
cancer cells based on type-I and type-II mechanisms, and the sensitization of …

Design of a Metallacycle‐Based Supramolecular Photosensitizer for In Vivo Image‐Guided Photodynamic Inactivation of Bacteria

Y Xu, W Tuo, L Yang, Y Sun, C Li, X Chen… - Angewandte …, 2022 - Wiley Online Library
Bacterial infection is one of the greatest threats to public health. In vivo real‐time monitoring
and effective treatment of infected sites through non‐invasive techniques, remain a …

Biomarker-activatable probes based on smart AIEgens for fluorescence and optoacoustic imaging

J Ouyang, L Sun, F Zeng, S Wu - Coordination Chemistry Reviews, 2022 - Elsevier
Fluorophores with aggregation-induced emission (AIE) are characterized by many
advantageous features for biomedical applications, including excellent photostability and …