Fungal infections represent a major, albeit neglected, public health threat with serious
medical and economic burdens globally. With unacceptably high mortality rates, invasive …

Background: Cross-resistance to medical azoles by exposure to azole pesticides is well
documented for Aspergillus family fungi but is poorly evaluated for other environmental …

Antifungal therapy, especially with the azoles, could promote the incidence of less
susceptible isolates of Cryptococcus neoformans and C. gattii species complexes (SC) …

Cryptococcus spp. are environmental fungi that first must adapt to the host environment
before they can cause life-threatening meningitis in immunocompromised patients. Host …

Ergosterol, the major sterol in fungal membranes, is critical for defining membrane fluidity
and regulating cellular processes. Although ergosterol synthesis has been well defined in …

Neuromeningeal cryptococcosis is a life-threatening infection of the central nervous system,
caused by encapsulated yeast belonging to the Cryptococcus neoformans and …

Cryptococcus neoformans has been designated as critical fungal pathogens by the World
Health Organization, mainly due to limited treatment options and the prevalence of …

Fusarium wilt caused by the fungal pathogen Fusarium oxysporum f. sp. ciceri (Foc) is a
devastating chickpea disease. Foc is a soil-borne pathogen that invades plants through …

Cryptococcus neoformans is an encapsulated yeast that can cause cryptococcosis and
cryptococcal meningitis, which conventional treatment involves antifungal drugs such as …

Trichoderma harzianum is a well-known biological control agent (BCA) that shows great
potential in controlling many pathogenic fungi. To screen for genes associated with …