Berberine: A novel therapeutic strategy for cancer

P Samadi, P Sarvarian, E Gholipour, KS Asenjan… - IUBMB …, 2020 - Wiley Online Library
Cancer, even currently, is one of the main reasons for mortality and morbidity, worldwide. In
recent years, a great deal of effort has been made to find efficient therapeutic strategies for …

Network pharmacology, molecular docking, and molecular dynamics simulation to elucidate the mechanism of anti-aging action of Tinospora cordifolia

A Bisht, D Tewari, S Kumar, S Chandra - Molecular Diversity, 2023 - Springer
Scientific research has demonstrated that Tinospora cordifolia acts as an anti-aging agent in
several experimental models, generating global interest in its underlying molecular …

Systems pharmacology reveals the mechanism of activity of Ge-Gen-Qin-Lian decoction against LPS-induced acute lung injury: a novel strategy for exploring active …

Z Ding, R Zhong, Y Yang, T Xia, W Wang… - Pharmacological …, 2020 - Elsevier
Acute lung injury (ALI), a severe and life-threatening inflammation of the lung, with high
morbidity and mortality, underscoring the urgent need for novel treatments. Ge-Gen-Qin-Lian …

Triterpenoid saponins from Ilex pubescens promote blood circulation in blood stasis syndrome by regulating sphingolipid metabolism and the PI3K/AKT/eNOS …

J Chen, D Cao, S Jiang, X Liu, W Pan, H Cui, W Yang… - Phytomedicine, 2022 - Elsevier
Background Blood stasis syndrome (BSS) is a severe disorder involving disturbances in
glycerophosphocholine metabolism. Ilex pubescens (IP) can regulate the levels of lipids …

Potential cytotoxic and anti-metastatic effects of berberine on gynaecological cancers with drug-associated resistance

H Mortazavi, B Nikfar, SA Esmaeili, F Rafieenia… - European journal of …, 2020 - Elsevier
Gynaecological disorders, such as cervical, ovarian, and endometrial cancers are the
second most prevalent cancer types in women worldwide. Therapeutic approaches for …

[HTML][HTML] In silico identification of natural products from Traditional Chinese Medicine for cancer immunotherapy

C Cai, Q Wu, H Hong, L He, Z Liu, Y Gu, S Zhang… - Scientific Reports, 2021 - nature.com
Advances in immunotherapy have revolutionized treatments in many types of cancer.
Traditional Chinese Medicine (TCM), which has a long history of clinical adjuvant …

Berberine inhibits tumour growth in vivo and in vitro through suppressing the lincROR-Wnt/β-catenin regulatory axis in colorectal cancer

S Li, C Shi, W Fu, J Zhang - Journal of Pharmacy and …, 2023 - academic.oup.com
Background Berberine, a non-prescription medicine clinically applied for diarrhoea and
gastroenteritis. Recent studies have demonstrated that it possesses anti-tumour properties …

[HTML][HTML] Natural products in digestive tract tumors metabolism: Functional and application prospects

P Xing, Y Zhong, X Cui, Z Liu, X Wu - Pharmacological Research, 2023 - Elsevier
Digestive tract diseases are presently the hotspot of clinical diagnosis and treatment, and
the incidence of digestive tract tumor is increasing annually. Surgery remains the main …

Berberine reverses epithelial-mesenchymal transition and modulates histone methylation in osteosarcoma cells

R Mishra, S Nathani, R Varshney, D Sircar… - Molecular Biology …, 2020 - Springer
Osteosarcoma is the most frequently occurring cancer in children as well as young
adolescents and the metastatic forms worsen this condition to a further great extent. The …

[HTML][HTML] Effect of Berberis vulgaris L. root extract on ifosfamide-induced in vivo toxicity and in vitro cytotoxicity

S Ilyas, R Tabasum, A Iftikhar, M Nazir, A Hussain… - Scientific reports, 2021 - nature.com
Ifosfamide is a widely used chemotherapeutic agent having broad-spectrum efficacy against
several tumors. However, nephro, hepato, neuro cardio, and hematological toxicities …